Literature DB >> 34128246

Recent advances (2019-2021) of capillary electrophoresis-mass spectrometry for multilevel proteomics.

Daoyang Chen1, Elijah N McCool1, Zhichang Yang1, Xiaojing Shen1, Rachele A Lubeckyj1, Tian Xu1, Qianjie Wang1, Liangliang Sun1.   

Abstract

Multilevel proteomics aims to delineate proteins at the peptide (bottom-up proteomics), proteoform (top-down proteomics), and protein complex (native proteomics) levels. Capillary electrophoresis-mass spectrometry (CE-MS) can achieve highly efficient separation and highly sensitive detection of complex mixtures of peptides, proteoforms, and even protein complexes because of its substantial technical progress. CE-MS has become a valuable alternative to the routinely used liquid chromatography-mass spectrometry for multilevel proteomics. This review summarizes the most recent (2019-2021) advances of CE-MS for multilevel proteomics regarding technological progress and biological applications. We also provide brief perspectives on CE-MS for multilevel proteomics at the end, highlighting some future directions and potential challenges.
© 2021 John Wiley & Sons Ltd.

Entities:  

Keywords:  capillary isoelectric focusing-mass spectrometry; capillary zone electrophoresis-mass spectrometry; multilevel proteomics; protein complex; proteoform

Year:  2021        PMID： 34128246      PMCID： PMC8671558          DOI： 10.1002/mas.21714

Source DB:  PubMed          Journal:  Mass Spectrom Rev        ISSN： 0277-7037            Impact factor:   10.946


  152 in total

1.  High sequence coverage of proteins isolated from liquid separations of breast cancer cells using capillary electrophoresis-time-of-flight MS and MALDI-TOF MS mapping.

Authors:  Kan Zhu; Jeongkwon Kim; Chul Yoo; Fred R Miller; David M Lubman
Journal:  Anal Chem       Date:  2003-11-15       Impact factor: 6.986

2.  CE-microreactor-CE-MS/MS for protein analysis.

Authors:  Regine M Schoenherr; Mingliang Ye; Michael Vannatta; Norman J Dovichi
Journal:  Anal Chem       Date:  2007-02-13       Impact factor: 6.986

3.  Online CIEF-ESI-MS in glycerol-water media with a view to hydrophobic protein applications.

Authors:  Meriem Mokaddem; Pierre Gareil; Anne Varenne
Journal:  Electrophoresis       Date:  2009-12       Impact factor: 3.535

4.  Capillary zone electrophoresis-tandem mass spectrometry for top-down proteomics using attapulgite nanoparticles functionalized separation capillaries.

Authors:  Tingting Wang; Daoyang Chen; Rachele A Lubeckyj; Xiaojing Shen; Zhichang Yang; Elijah N McCool; Xiaoqiang Qiao; Liangliang Sun
Journal:  Talanta       Date:  2019-04-21       Impact factor: 6.057

5.  Evaluation of on-line solid-phase extraction capillary electrophoresis-mass spectrometry with a nanoliter valve for the analysis of peptide biomarkers.

Authors:  Roger Pero-Gascon; Fernando Benavente; Christian Neusüß; Victoria Sanz-Nebot
Journal:  Anal Chim Acta       Date:  2020-09-22       Impact factor: 6.558

6.  Capillary zone electrophoresis-tandem mass spectrometry using ultraviolet photodissociation (213 nm) for large-scale top-down proteomics.

Authors:  Elijah N McCool; Daoyang Chen; Wenxue Li; Yansheng Liu; Liangliang Sun
Journal:  Anal Methods       Date:  2019-05-07       Impact factor: 2.896

7.  A Middle-Up Approach with Online Capillary Isoelectric Focusing/Mass Spectrometry for In-Depth Characterization of Cetuximab Charge Heterogeneity.

Authors:  Jun Dai; Yingru Zhang
Journal:  Anal Chem       Date:  2018-12-04       Impact factor: 6.986

8.  Structure-property studies on carbohydrate-derived polymers for use as protein-resistant biomaterials.

Authors:  Mark Metzke; Zhibin Guan
Journal:  Biomacromolecules       Date:  2007-12-14       Impact factor: 6.988

9.  Rapid and site-specific deep phosphoproteome profiling by data-independent acquisition without the need for spectral libraries.

Authors:  Dorte B Bekker-Jensen; Oliver M Bernhardt; Alexander Hogrebe; Ana Martinez-Val; Lynn Verbeke; Tejas Gandhi; Christian D Kelstrup; Lukas Reiter; Jesper V Olsen
Journal:  Nat Commun       Date:  2020-02-07       Impact factor: 14.919

10.  Integrative proteomics reveals principles of dynamic phosphosignaling networks in human erythropoiesis.

Authors:  Özge Karayel; Peng Xu; Isabell Bludau; Senthil Velan Bhoopalan; Yu Yao; Freitas Colaco Ana Rita; Alberto Santos; Brenda A Schulman; Arno F Alpi; Mitchell J Weiss; Matthias Mann
Journal:  Mol Syst Biol       Date:  2020-12       Impact factor: 11.429
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  3 in total

1.  Evaluation of Machine Learning Models for Proteoform Retention and Migration Time Prediction in Top-Down Mass Spectrometry.

Authors:  Wenrong Chen; Elijah N McCool; Liangliang Sun; Yong Zang; Xia Ning; Xiaowen Liu
Journal:  J Proteome Res       Date:  2022-05-26       Impact factor: 5.370

2.  Laser capture microdissection-capillary zone electrophoresis-tandem mass spectrometry (LCM-CZE-MS/MS) for spatially resolved top-down proteomics: a pilot study of zebrafish brain.

Authors:  Rachele A Lubeckyj; Liangliang Sun
Journal:  Mol Omics       Date:  2022-02-21

Review 3.  Immunoaffinity Capillary Electrophoresis in the Era of Proteoforms, Liquid Biopsy and Preventive Medicine: A Potential Impact in the Diagnosis and Monitoring of Disease Progression.

Authors:  Norberto A Guzman; Daniel E Guzman
Journal:  Biomolecules       Date:  2021-10-01
  3 in total

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