Ricardo Larrainzar-Garijo1,2, Adolfo Díez-Pérez3, Esther Fernández-Tormos4, Daniel Prieto-Alhambra3,5,6. 1. Orthopadic and Trauma Department, Hospital Universitario Infanta Leonor, C/ Gran Via Este 80, 28031, Madrid, Spain. rlarrainzar@gmail.com. 2. Departamento Cirugía. Facultad de Medicina, Universidad Complutense, Madrid, Spain. rlarrainzar@gmail.com. 3. Musculoskeletal Research Unit, IMIM-Parc Salut Mar, CIBERFES, Universitat Autonoma de Barcelona, Doctor Aiguader 88, 20, 08003, Barcelona, Spain. 4. Orthopadic and Trauma Department, Hospital Universitario Infanta Leonor, C/ Gran Via Este 80, 28031, Madrid, Spain. 5. GREMPAL (Grup de Recerca en Epidemiologia de Les Malalties Prevalents de L'Aparell Locomotor) Research Group, Av Gran Via de Les Corts Catalanes, CIBERFES, IDIAP Jordi Gol (Universitat Autonoma de Barcelona) Instituto 16 de Salud Carlos III, 58708007, Barcelona, Atic, Spain. 6. Musculoskeletal Pharmaco and Device Epidemiology - Centre for Statistics in Medicine Nuffield, Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Windmill Road, Oxford, OX3 7LD, UK.
Abstract
INTRODUCTION: The risk factors for a second nonsimultaneous hip fracture are unclear, and in general, it is empirically assumed that they are similar to those associated with the first hip fracture. We aimed to determine the incidence of a second hip fracture and define the characteristics of the patients sustaining the event in a prospective cohort study in a Spanish population. MATERIALS AND METHODS: We conducted a multicentric, prospective cohort study in a representative sample of 45 hospitals from 15 autonomic regions in Spain. In total, the study included 994 patients. One hundred and one patients presented a nonsimultaneous contralateral hip fracture, constituting the intervention group. The remaining 893 patients presenting with a hip fracture formed the control group. The main outcome measures of this study were sociodemographic characteristics of the patient, comorbid conditions, and baseline and postfracture clinical outcomes (inpatient complications and acute mortality). RESULTS: The key fracture risk factors were a history of fragility fractures, the need for assistance when walking outdoors and a history of falls. There were no associations between the groups in any of the common fragility risk factors, including rheumatoid arthritis, secondary osteoporosis, or steroid consumption. The results showed that patients suffering a nonsimultaneous hip fracture had an increased risk of mortality after discharge compared with the control group. CONCLUSION: A nonsimultaneous second hip fracture leads to a near-significant increase in four-month mortality. In our study, this fracture was associated with a history of falls, prior fragility fractures, and the need for a walking aid.
INTRODUCTION: The risk factors for a second nonsimultaneous hip fracture are unclear, and in general, it is empirically assumed that they are similar to those associated with the first hip fracture. We aimed to determine the incidence of a second hip fracture and define the characteristics of the patients sustaining the event in a prospective cohort study in a Spanish population. MATERIALS AND METHODS: We conducted a multicentric, prospective cohort study in a representative sample of 45 hospitals from 15 autonomic regions in Spain. In total, the study included 994 patients. One hundred and one patients presented a nonsimultaneous contralateral hip fracture, constituting the intervention group. The remaining 893 patients presenting with a hip fracture formed the control group. The main outcome measures of this study were sociodemographic characteristics of the patient, comorbid conditions, and baseline and postfracture clinical outcomes (inpatient complications and acute mortality). RESULTS: The key fracture risk factors were a history of fragility fractures, the need for assistance when walking outdoors and a history of falls. There were no associations between the groups in any of the common fragility risk factors, including rheumatoid arthritis, secondary osteoporosis, or steroid consumption. The results showed that patients suffering a nonsimultaneous hip fracture had an increased risk of mortality after discharge compared with the control group. CONCLUSION: A nonsimultaneous second hip fracture leads to a near-significant increase in four-month mortality. In our study, this fracture was associated with a history of falls, prior fragility fractures, and the need for a walking aid.
Authors: E C Folbert; J H Hegeman; M Vermeer; E M Regtuijt; D van der Velde; H J Ten Duis; J P Slaets Journal: Osteoporos Int Date: 2016-07-21 Impact factor: 4.507
Authors: Tone K Omsland; Nina Emaus; Grethe S Tell; Luai A Ahmed; Jacqueline R Center; Nguyen D Nguyen; Clara G Gjesdal; Siri Forsmo; Berit Schei; Anne Johanne Søgaard; Haakon E Meyer Journal: Bone Date: 2012-09-18 Impact factor: 4.398
Authors: Shih-Hsun Shen; Kuo-Chin Huang; Yao-Hung Tsai; Tien-Yu Yang; Mel S Lee; Steve W N Ueng; Robert W W Hsu Journal: J Am Med Dir Assoc Date: 2014-07-10 Impact factor: 4.669