Literature DB >> 34124179

What Are the Most Challenging Aspects of Inflammatory Bowel Disease? An International Survey of Gastroenterologists Comparing Developed and Developing Countries.

Richard B Gearry1, Andrew M McCombie1, Morten Vatn2, David T Rubin3, Flavio Steinwurz4, Edward V Loftus5, Wolfgang Kruis6, Curt Tysk7, Jean-Frederic Colombel8, Siew C Ng9, Gert Van Assche10, Charles N Bernstein11.   

Abstract

BACKGROUND AND AIMS: As inflammatory bowel disease (IBD) becomes more prevalent, the challenges that gastroenterologists face in managing these patients evolve. We aimed to describe the most important challenges facing gastroenterologists from around the world and compare these between those working in developed and developing countries.
METHODS: An online questionnaire was developed, and a link distributed to gastroenterologists. Data were analyzed descriptively using Friedman and Wilcoxon matched-pair signed rank tests to compare rankings for responses. Mann-Whitney U tests were used to compare rankings between responses from gastroenterologists from developed and developing countries. Lower scores reflected greater challenges.
RESULTS: Of 872 who started, 397 gastroenterologists (45.5%) completed the survey. Respondents represented 65 countries (226 [56.9%] from developed countries). Overall, the challenge ranked most important (smallest number) was increasing IBD prevalence (13.6%). There were significant differences in mean ranking scores for many simple aspects of care for those from developing countries compared to providers from developed countries, such as access to simple IBD treatments (5.52 vs. 6.02, p = 0.01), access to anti-TNF drugs including dose escalation (3.33 vs. 3.93, p < 0.01), access to good stoma care (2.57 vs. 3.03, p < 0.001), access to therapeutic drug monitoring (1.47 vs. 1.84, p < 0.001), and access to care for people from low socioeconomic status (2.77 vs. 3.37, p < 0.001).
CONCLUSIONS: Increasing IBD prevalence is seen by gastroenterologists as the greatest challenge facing them. There are significant differences between the IBD challenges facing gastroenterologists from developed and developing countries that reflect inequities in access to health care.
Copyright © 2021 by S. Karger AG, Basel.

Entities:  

Keywords:  Challenges; Crohn's disease; Inflammatory bowel diseases; Ulcerative colitis

Year:  2021        PMID: 34124179      PMCID: PMC8160566          DOI: 10.1159/000512310

Source DB:  PubMed          Journal:  Inflamm Intest Dis        ISSN: 2296-9365


  13 in total

Review 1.  The global burden of IBD: from 2015 to 2025.

Authors:  Gilaad G Kaplan
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2015-09-01       Impact factor: 46.802

Review 2.  Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review.

Authors:  Natalie A Molodecky; Ing Shian Soon; Doreen M Rabi; William A Ghali; Mollie Ferris; Greg Chernoff; Eric I Benchimol; Remo Panaccione; Subrata Ghosh; Herman W Barkema; Gilaad G Kaplan
Journal:  Gastroenterology       Date:  2011-10-14       Impact factor: 22.682

3.  World Gastroenterology Organization Practice Guidelines for the diagnosis and management of IBD in 2010.

Authors:  Charles N Bernstein; Michael Fried; J H Krabshuis; Henry Cohen; R Eliakim; Suleiman Fedail; Richard Gearry; K L Goh; Saheed Hamid; Aamir Ghafor Khan; A W LeMair; Qin Ouyang; J F Rey; Ajit Sood; Flavio Steinwurz; Ole O Thomsen; Alan Thomson; Gillian Watermeyer
Journal:  Inflamm Bowel Dis       Date:  2010-01       Impact factor: 5.325

4.  Race Differences in Initial Presentation, Early Treatment, and 1-year Outcomes of Pediatric Crohn's Disease: Results from the ImproveCareNow Network.

Authors:  Jennifer L Dotson; Michele Cho; Josh Bricker; Michael D Kappelman; Deena J Chisolm; Gitit Tomer; Wallace V Crandall
Journal:  Inflamm Bowel Dis       Date:  2017-05       Impact factor: 5.325

5.  Rising Incidence of Inflammatory Bowel Disease in Canterbury, New Zealand.

Authors:  Heidi Y Su; Vikesh Gupta; Andrew S Day; Richard B Gearry
Journal:  Inflamm Bowel Dis       Date:  2016-09       Impact factor: 5.325

6.  Progression of Inflammatory Bowel Diseases Throughout Latin America and the Caribbean: a Systematic Review.

Authors:  Paulo Gustavo Kotze; Fox E Underwood; Aderson Omar Mourão Cintra Damião; Jose Geraldo P Ferraz; Rogerio Saad-Hossne; Martin Toro; Beatriz Iade; Francisco Bosques-Padilla; Fábio Vieira Teixeira; Fabian Juliao-Banos; Daniela Simian; Subrata Ghosh; Remo Panaccione; Siew C Ng; Gilaad G Kaplan
Journal:  Clin Gastroenterol Hepatol       Date:  2019-06-25       Impact factor: 11.382

7.  Incidence and phenotype of inflammatory bowel disease based on results from the Asia-pacific Crohn's and colitis epidemiology study.

Authors:  Siew C Ng; Whitney Tang; Jessica Y Ching; May Wong; Chung Mo Chow; A J Hui; T C Wong; Vincent K Leung; Steve W Tsang; Hon Ho Yu; Mo Fong Li; Ka Kei Ng; Michael A Kamm; Corrie Studd; Sally Bell; Rupert Leong; H Janaka de Silva; Anuradhani Kasturiratne; M N F Mufeena; Khoon Lin Ling; Choon Jin Ooi; Poh Seng Tan; David Ong; Khean L Goh; Ida Hilmi; Pises Pisespongsa; Sathaporn Manatsathit; Rungsun Rerknimitr; Satimai Aniwan; Yu Fang Wang; Qin Ouyang; Zhirong Zeng; Zhenhua Zhu; Min Hu Chen; Pin Jin Hu; Kaichun Wu; Xin Wang; Marcellus Simadibrata; Murdani Abdullah; Justin Cy Wu; Joseph J Y Sung; Francis K L Chan
Journal:  Gastroenterology       Date:  2013-04-09       Impact factor: 22.682

Review 8.  Worldwide incidence and prevalence of inflammatory bowel disease in the 21st century: a systematic review of population-based studies.

Authors:  Siew C Ng; Hai Yun Shi; Nima Hamidi; Fox E Underwood; Whitney Tang; Eric I Benchimol; Remo Panaccione; Subrata Ghosh; Justin C Y Wu; Francis K L Chan; Joseph J Y Sung; Gilaad G Kaplan
Journal:  Lancet       Date:  2017-10-16       Impact factor: 79.321

Review 9.  Epidemiology of Inflammatory Bowel Disease in India: The Great Shift East.

Authors:  Saurabh Kedia; Vineet Ahuja
Journal:  Inflamm Intest Dis       Date:  2017-04-08

10.  The Impact of Inflammatory Bowel Disease in Canada 2018: IBD Research Landscape in Canada.

Authors:  Keeley L Rose; Philip M Sherman; Jane Cooke-Lauder; Mina Mawani; Eric I Benchimol; Gilaad G Kaplan; Charles N Bernstein; Alain Bitton; Sanjay K Murthy; Geoffrey C Nguyen; Kate Lee
Journal:  J Can Assoc Gastroenterol       Date:  2018-11-02
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