Literature DB >> 3412376

Chitinase in female Onchocerca gibsoni and its inhibition by allosamidin.

G W Gooday1, L J Brydon, L H Chappell.   

Abstract

Chitinase activity has been detected in female worms of Onchocerca gibsoni. With 3,4-dinitrophenyl-tetra-N-acetylchitotetraoside as substrate 50% of maximum activity was achieved at about 25 microM substrate, with inhibition above 50 microM substrate. The antibiotic allosamidin very strongly inhibited the chitinase activity, 50% inhibition being achieved by 200 pM allosamidin in the presence of 45 microM substrate.

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Year:  1988        PMID： 3412376     DOI： 10.1016/0166-6851(88)90077-1

Source DB:  PubMed          Journal:  Mol Biochem Parasitol        ISSN： 0166-6851            Impact factor:   1.759


  7 in total

Review 1.  What's new in chitinase research?

Authors:  J Flach; P E Pilet; P Jollès
Journal:  Experientia       Date:  1992-08-15

2.  Chitinase activity in germinating cells of Mucor rouxii.

Authors:  M Pedraza-Reyes; E Lopez-Romero
Journal:  Antonie Van Leeuwenhoek       Date:  1991-04       Impact factor: 2.271

3.  Molecular dysexpression in gastric cancer revealed by integrated analysis of transcriptome data.

Authors:  Xiaomei Li; Weiwei Dong; Xueling Qu; Huixia Zhao; Shuo Wang; Yixin Hao; Qiuwen Li; Jianhua Zhu; Min Ye; Wenhua Xiao
Journal:  Oncol Lett       Date:  2017-03-03       Impact factor: 2.967

4.  Transmission-blocking activity of a chitinase inhibitor and activation of malarial parasite chitinase by mosquito protease.

Authors:  M Shahabuddin; T Toyoshima; M Aikawa; D C Kaslow
Journal:  Proc Natl Acad Sci U S A       Date:  1993-05-01       Impact factor: 11.205

5.  Transmission-blocking antibodies recognize microfilarial chitinase in brugian lymphatic filariasis.

Authors:  J A Fuhrman; W S Lane; R F Smith; W F Piessens; F B Perler
Journal:  Proc Natl Acad Sci U S A       Date:  1992-03-01       Impact factor: 11.205

6.  Cloning and characterization of a potentially protective chitinase-like recombinant antigen from Wuchereria bancrofti.

Authors:  N Raghavan; D O Freedman; P C Fitzgerald; T R Unnasch; E A Ottesen; T B Nutman
Journal:  Infect Immun       Date:  1994-05       Impact factor: 3.441

7.  Chitinase is stored and secreted from the inner body of microfilariae and has a role in exsheathment in the parasitic nematode Brugia malayi.

Authors:  Yang Wu; Gillian Preston; Albert E Bianco
Journal:  Mol Biochem Parasitol       Date:  2008-06-20       Impact factor: 1.759
  7 in total

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