Literature DB >> 34119456

Helicobacter pylori: a stealth assassin.

Lydia E Wroblewski1, Richard M Peek2.   

Abstract

Helicobacter pylori is a pathogen that confers the highest known risk for gastric cancer. Research directed at understanding the pathogenesis of H. pylori is crucial to identify colonized persons that may subsequently develop neoplasia. Imai et al. describe how H. pylori elicits BRCAness and endows epithelial cells with the ability to evade apoptosis.
Copyright © 2021 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  BRCAness; CagA; Helicobacter pylori; P53; PAR1b; gastric cancer

Mesh:

Substances:

Year:  2021        PMID: 34119456      PMCID: PMC8708809          DOI: 10.1016/j.trecan.2021.05.007

Source DB:  PubMed          Journal:  Trends Cancer        ISSN: 2405-8025


  10 in total

1.  Helicobacter pylori CagA elicits BRCAness to induce genome instability that may underlie bacterial gastric carcinogenesis.

Authors:  Satoshi Imai; Takuya Ooki; Naoko Murata-Kamiya; Daisuke Komura; Kamrunnesa Tahmina; Weida Wu; Atsushi Takahashi-Kanemitsu; Christopher Takaya Knight; Akiko Kunita; Nobumi Suzuki; Adriana A Del Valle; Mayo Tsuboi; Masahiro Hata; Yoku Hayakawa; Naomi Ohnishi; Koji Ueda; Masashi Fukayama; Tetsuo Ushiku; Shumpei Ishikawa; Masanori Hatakeyama
Journal:  Cell Host Microbe       Date:  2021-05-06       Impact factor: 21.023

2.  Regulation of p53 tumor suppressor by Helicobacter pylori in gastric epithelial cells.

Authors:  Jinxiong Wei; Toni A Nagy; Anna Vilgelm; Elena Zaika; Seth R Ogden; Judith Romero-Gallo; Maria B Piazuelo; Pelayo Correa; Mary K Washington; Wael El-Rifai; Richard M Peek; Alexander Zaika
Journal:  Gastroenterology       Date:  2010-06-12       Impact factor: 22.682

3.  Mutations in the p53 Tumor Suppressor Gene: Important Milestones at the Various Steps of Tumorigenesis.

Authors:  Noa Rivlin; Ran Brosh; Moshe Oren; Varda Rotter
Journal:  Genes Cancer       Date:  2011-04

Review 4.  Gastritis and gastric cancer. Western countries.

Authors:  P Sipponen; B J Marshall
Journal:  Gastroenterol Clin North Am       Date:  2000-09       Impact factor: 3.806

Review 5.  Pathobiology of Helicobacter pylori-Induced Gastric Cancer.

Authors:  Manuel Amieva; Richard M Peek
Journal:  Gastroenterology       Date:  2015-09-16       Impact factor: 22.682

6.  Global surveillance of trends in cancer survival 2000-14 (CONCORD-3): analysis of individual records for 37 513 025 patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries.

Authors:  Claudia Allemani; Tomohiro Matsuda; Veronica Di Carlo; Rhea Harewood; Melissa Matz; Maja Nikšić; Audrey Bonaventure; Mikhail Valkov; Christopher J Johnson; Jacques Estève; Olufemi J Ogunbiyi; Gulnar Azevedo E Silva; Wan-Qing Chen; Sultan Eser; Gerda Engholm; Charles A Stiller; Alain Monnereau; Ryan R Woods; Otto Visser; Gek Hsiang Lim; Joanne Aitken; Hannah K Weir; Michel P Coleman
Journal:  Lancet       Date:  2018-01-31       Impact factor: 79.321

Review 7.  Human gastric carcinogenesis: a multistep and multifactorial process--First American Cancer Society Award Lecture on Cancer Epidemiology and Prevention.

Authors:  P Correa
Journal:  Cancer Res       Date:  1992-12-15       Impact factor: 12.701

8.  Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.

Authors:  Freddie Bray; Jacques Ferlay; Isabelle Soerjomataram; Rebecca L Siegel; Lindsey A Torre; Ahmedin Jemal
Journal:  CA Cancer J Clin       Date:  2018-09-12       Impact factor: 508.702

9.  Cancer suppression by the chromosome custodians, BRCA1 and BRCA2.

Authors:  Ashok R Venkitaraman
Journal:  Science       Date:  2014-03-28       Impact factor: 47.728

10.  p53 mutations associated with aging-related rise in cancer incidence rates.

Authors:  Richard B Richardson
Journal:  Cell Cycle       Date:  2013-07-01       Impact factor: 4.534

  10 in total
  1 in total

Review 1.  Helicobacter Pylori and Autoimmune Diseases: Involving Multiple Systems.

Authors:  Li Wang; Zheng-Min Cao; Li-Li Zhang; Xin-Can Dai; Zhen-Ju Liu; Yi-Xian Zeng; Xin-Ye Li; Qing-Juan Wu; Wen-Liang Lv
Journal:  Front Immunol       Date:  2022-02-10       Impact factor: 7.561

  1 in total

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