Literature DB >> 3411391

Nonfluorescent dicentric Y in males with hypospadias.

M Drummond-Borg1, R A Pagon, C M Bradley, J Nordlund, D Salk.   

Abstract

We report three boys with severe hypospadias and bilaterally palpable testes with abnormalities of the Y chromosome detected by Q-banding. Severe hypospadias with palpable testes is an unusual presentation for Y chromosome abnormalities. Based on our experience, we recommend that boys with this phenotype undergo complete cytogenetic evaluation, because Y chromosome abnormalities prompt additional management concerns.

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Year:  1988        PMID: 3411391     DOI: 10.1016/s0022-3476(88)80630-9

Source DB:  PubMed          Journal:  J Pediatr        ISSN: 0022-3476            Impact factor:   4.406


  1 in total

Review 1.  Isodicentric Y chromosome: cytogenetic, molecular and clinical studies and review of the literature.

Authors:  C M Tuck-Muller; H Chen; J E Martínez; C C Shen; S Li; C Kusyk; D A Batista; Y M Bhatnagar; E Dowling; W Wertelecki
Journal:  Hum Genet       Date:  1995-07       Impact factor: 4.132

  1 in total

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