Literature DB >> 3411332

Primary structure of neuromedin U from the rat.

J M Conlon1, J Domin, L Thim, V DiMarzo, H R Morris, S R Bloom.   

Abstract

The primary structure of neuromedin U from the rat ileum was established as: Tyr-Lys-Val-Asn-Glu5-Tyr-Gln-Gly-Pro-Val10-Ala-Pro-Ser-Gly-+ ++Gly15-Phe-Phe-Leu- Phe-Arg20-Pro-Arg-Asn.NH2. There was no evidence for microheterogeneity. This amino acid sequence contains two deletions and nine substitutions compared with the neuromedin U-25 from the pig. In particular, the replacement of the Arg16-Arg17 processing site in the porcine peptide by Gly14-Gly15 in the rat means that a peptide corresponding to neuromedin U-8 was not found in the rat intestine.

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Year:  1988        PMID： 3411332     DOI： 10.1111/j.1471-4159.1988.tb01837.x

Source DB:  PubMed          Journal:  J Neurochem        ISSN： 0022-3042            Impact factor:   5.372


  9 in total

1.  Central administration of neuromedin U activates neurons in ventrobasal hypothalamus and brainstem.

Authors:  M Niimi; K Murao; T Taminato
Journal:  Endocrine       Date:  2001-12       Impact factor: 3.633

2.  Neuromedin U-like immunoreactivity in the thyroid gland of the rat.

Authors:  J Domin; A M Al-Madani; M Desperbasques; A E Bishop; J M Polak; S R Bloom
Journal:  Cell Tissue Res       Date:  1990-04       Impact factor: 5.249

3.  Localisation of NMU1R and NMU2R in human and rat central nervous system and effects of neuromedin-U following central administration in rats.

Authors:  Jane Gartlon; Philip Szekeres; Mark Pullen; Henry M Sarau; Nambi Aiyar; Usman Shabon; David Michalovich; Klaudia Steplewski; Cathy Ellis; Nabil Elshourbagy; Mark Duxon; Tracey E Ashmeade; David C Harrison; Paul Murdock; Shelagh Wilson; Abdel Ennaceur; Alan Atkins; Christian Heidbreder; Jim J Hagan; A Jackie Hunter; Declan N C Jones
Journal:  Psychopharmacology (Berl)       Date:  2004-06-16       Impact factor: 4.530

4.  Species-dependent smooth muscle contraction to Neuromedin U and determination of the receptor subtypes mediating contraction using NMU1 receptor knockout mice.

Authors:  Clodagh E Prendergast; Magda F Morton; Katherine W Figueroa; Xiaodong Wu; Nigel P Shankley
Journal:  Br J Pharmacol       Date:  2006-04       Impact factor: 8.739

5.  Methamphetamine-induced dopamine-independent alterations in striatal gene expression in the 6-hydroxydopamine hemiparkinsonian rats.

Authors:  Jean Lud Cadet; Christie Brannock; Irina N Krasnova; Bruce Ladenheim; Michael T McCoy; Jenny Chou; Elin Lehrmann; William H Wood; Kevin G Becker; Yun Wang
Journal:  PLoS One       Date:  2010-12-13       Impact factor: 3.240

6.  Moniezia benedeni infection enhances neuromedin U (NMU) expression in sheep (Ovis aries) small intestine.

Authors:  Wan-Ling Yao; Li-Ping Liu; Yan-Qiao Wen; Bao-Shan Wang; Jia-Qi Dong; Wan-Hong He; Xi-Ping Fan; Wen-Hui Wang; Wang-Dong Zhang
Journal:  BMC Vet Res       Date:  2022-04-19       Impact factor: 2.792

Review 7.  Neuromedin U: potential roles in immunity and inflammation.

Authors:  Yuan Ye; Zongan Liang; Luzheng Xue
Journal:  Immunology       Date:  2020-09-16       Impact factor: 7.397

8.  Neuromedins U and S involvement in the regulation of the hypothalamo-pituitary-adrenal axis.

Authors:  Ludwik K Malendowicz; Agnieszka Ziolkowska; Marcin Rucinski
Journal:  Front Endocrinol (Lausanne)       Date:  2012-12-05       Impact factor: 5.555

9.  Negative regulation of neuromedin U mRNA expression in the rat pars tuberalis by melatonin.

Authors:  Sayaka Aizawa; Ichiro Sakata; Mai Nagasaka; Yuriko Higaki; Takafumi Sakai
Journal:  PLoS One       Date:  2013-07-02       Impact factor: 3.240
  9 in total

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