Literature DB >> 3411213

Necrotizing external otitis treated with ciprofloxacin. A case report.

F Sabater1, J Mensa, J Doménech, M Loncá, M Carulla.   

Abstract

Necrotizing (malignant) external otitis is a severe infection caused by Pseudomonas aeruginosa which occurs mainly in elderly diabetics or in immuno-depressed patients (Chandler, 1968). The management of this condition requires the association between an aminoglycoside antibiotic and an antipseudomonal beta-lactamic, given parenterally during a 4 to 6 week period. Sometimes it is necessary to continue the therapy for months until there is no evidence of residual disease (Strauss et al., 1982). Ciprofloxacin is a quinolone with antipseudomonal activity which can be taken orally, and it is a useful alternative to the current treatment. The authors report a case of necrotizing external otitis which was successfully treated with ciprofloxacin.

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Year:  1988        PMID: 3411213     DOI: 10.1017/s0022215100105857

Source DB:  PubMed          Journal:  J Laryngol Otol        ISSN: 0022-2151            Impact factor:   1.469


  3 in total

Review 1.  Ciprofloxacin. A review of its pharmacological profile and therapeutic use in the elderly.

Authors:  L R Wiseman; J A Balfour
Journal:  Drugs Aging       Date:  1994-02       Impact factor: 3.923

Review 2.  Optimum management of the discharging ear.

Authors:  J Ruddy; R C Bickerton
Journal:  Drugs       Date:  1992-02       Impact factor: 9.546

Review 3.  Use of quinolones for treatment of ear and eye infections.

Authors:  M Barza
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1991-04       Impact factor: 3.267

  3 in total

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