| Literature DB >> 3411213 |
F Sabater1, J Mensa, J Doménech, M Loncá, M Carulla.
Abstract
Necrotizing (malignant) external otitis is a severe infection caused by Pseudomonas aeruginosa which occurs mainly in elderly diabetics or in immuno-depressed patients (Chandler, 1968). The management of this condition requires the association between an aminoglycoside antibiotic and an antipseudomonal beta-lactamic, given parenterally during a 4 to 6 week period. Sometimes it is necessary to continue the therapy for months until there is no evidence of residual disease (Strauss et al., 1982). Ciprofloxacin is a quinolone with antipseudomonal activity which can be taken orally, and it is a useful alternative to the current treatment. The authors report a case of necrotizing external otitis which was successfully treated with ciprofloxacin.Entities:
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Year: 1988 PMID: 3411213 DOI: 10.1017/s0022215100105857
Source DB: PubMed Journal: J Laryngol Otol ISSN: 0022-2151 Impact factor: 1.469