Literature DB >> 34110786

Antimicrobial Susceptibility Testing of Antimicrobial Peptides Requires New and Standardized Testing Structures.

Marita Meurer1,2, Deborah A O'Neil3, Emma Lovie3, Laura Simpson3, Marcelo D T Torres4,5,6, Cesar de la Fuente-Nunez4,5,6, Alfredo M Angeles-Boza7,8, Christin Kleinsorgen9, Derry K Mercer3, Maren von Köckritz-Blickwede1,2.   

Abstract

The need for optimized as well as standardized test systems of novel antimicrobial peptides (AMPs) was discussed by experts in the field at the International Meeting on Antimicrobial Peptides (IMAP) 2017 and the 2019 Gordon Research Conference (GRC) on Antimicrobial Peptides, and a survey related to this topic was circulated to participants to collate opinions. The survey included questions ranging from the relevance of susceptibility testing for understanding the mode of action of AMPs, to the importance of optimization and a degree of standardization of test methods and their clinical relevance. Based on the survey results, suggestions for future improvements in the research field are made.

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Year:  2021        PMID: 34110786      PMCID: PMC8764967          DOI: 10.1021/acsinfecdis.1c00210

Source DB:  PubMed          Journal:  ACS Infect Dis        ISSN: 2373-8227            Impact factor:   5.084


  14 in total

Review 1.  The role of cationic antimicrobial peptides in innate host defences.

Authors:  R E Hancock; G Diamond
Journal:  Trends Microbiol       Date:  2000-09       Impact factor: 17.079

Review 2.  Tryptophan- and arginine-rich antimicrobial peptides: structures and mechanisms of action.

Authors:  David I Chan; Elmar J Prenner; Hans J Vogel
Journal:  Biochim Biophys Acta       Date:  2006-04-21

Review 3.  Induction of non-lamellar lipid phases by antimicrobial peptides: a potential link to mode of action.

Authors:  Evan F Haney; Safia Nathoo; Hans J Vogel; Elmar J Prenner
Journal:  Chem Phys Lipids       Date:  2010-01       Impact factor: 3.329

Review 4.  Natural roles of antimicrobial peptides in microbes, plants and animals.

Authors:  Gergely Maróti; Attila Kereszt; Eva Kondorosi; Peter Mergaert
Journal:  Res Microbiol       Date:  2011-02-12       Impact factor: 3.992

Review 5.  Bacterial membrane lipids in the action of antimicrobial agents.

Authors:  Richard M Epand; Raquel F Epand
Journal:  J Pept Sci       Date:  2010-11-30       Impact factor: 1.905

Review 6.  Next-generation precision antimicrobials: towards personalized treatment of infectious diseases.

Authors:  Cesar de la Fuente-Nunez; Marcelo Dt Torres; Francisco Jm Mojica; Timothy K Lu
Journal:  Curr Opin Microbiol       Date:  2017-06-14       Impact factor: 7.934

7.  Indolicidin action on membrane permeability: carrier mechanism versus pore formation.

Authors:  Tatyana I Rokitskaya; Nikolay I Kolodkin; Elena A Kotova; Yuri N Antonenko
Journal:  Biochim Biophys Acta       Date:  2010-09-17

Review 8.  New strategies for novel antibiotics: peptides targeting bacterial cell membranes.

Authors:  Karl Lohner
Journal:  Gen Physiol Biophys       Date:  2009-06       Impact factor: 1.512

9.  Predicting drug resistance evolution: insights from antimicrobial peptides and antibiotics.

Authors:  Guozhi Yu; Desiree Y Baeder; Roland R Regoes; Jens Rolff
Journal:  Proc Biol Sci       Date:  2018-03-14       Impact factor: 5.349

10.  Integrated evolutionary analysis reveals antimicrobial peptides with limited resistance.

Authors:  Réka Spohn; Lejla Daruka; Viktória Lázár; Ana Martins; Fanni Vidovics; Gábor Grézal; Orsolya Méhi; Bálint Kintses; Mónika Számel; Pramod K Jangir; Bálint Csörgő; Ádám Györkei; Zoltán Bódi; Anikó Faragó; László Bodai; Imre Földesi; Diána Kata; Gergely Maróti; Bernadett Pap; Roland Wirth; Balázs Papp; Csaba Pál
Journal:  Nat Commun       Date:  2019-10-04       Impact factor: 14.919

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  2 in total

1.  Measuring Thousands of Single-Vesicle Leakage Events Reveals the Mode of Action of Antimicrobial Peptides.

Authors:  Kareem Al Nahas; Marcus Fletcher; Katharine Hammond; Christian Nehls; Jehangir Cama; Maxim G Ryadnov; Ulrich F Keyser
Journal:  Anal Chem       Date:  2022-06-27       Impact factor: 8.008

2.  An ultrasensitive microfluidic approach reveals correlations between the physico-chemical and biological activity of experimental peptide antibiotics.

Authors:  Jehangir Cama; Kareem Al Nahas; Marcus Fletcher; Katharine Hammond; Maxim G Ryadnov; Ulrich F Keyser; Stefano Pagliara
Journal:  Sci Rep       Date:  2022-03-07       Impact factor: 4.996

  2 in total

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