Literature DB >> 34109282

Successful Treatment of Full-Thickness Macular Hole in Polypoidal Choroidal Vasculopathy with Anti-VEGF Therapy.

Aaron Lindeke-Myers1, Gregg T Kokame2,3,4,5,6, Steven Yeh1,7, Jessica Shantha1,7.   

Abstract

PURPOSE: To report a case of an 86-year-old man with a full thickness macular hole (FTMH) secondary to polypoidal choroidal vasculopathy (PCV) treated with bevacizumab.
METHODS: A retrospective case report is presented.
RESULTS: An 86-year-old male presented with a five-month history of metamorphopsia and decreased vision in his right eye and was found to have active exudation secondary to PCV with a concurrent FTMH. After four treatments with intravitreal bevacizumab, the FTMH resolved without surgical intervention.
CONCLUSIONS: The patient's FTMH resolved with solely pharmacologic treatment as a result of treating his PCV with intravitreal bevacizumab. MH formation secondary to PCV is a rare finding, but may be successfully treated with pharmacologic therapy without surgical intervention.

Entities:  

Keywords:  Polypoidal choroidal vasculopathy (PCV); bevacizumab; full thickness macular hole (FTMH); macular hole (MH)

Year:  2020        PMID: 34109282      PMCID: PMC8186496          DOI: 10.1177/2474126420909706

Source DB:  PubMed          Journal:  J Vitreoretin Dis        ISSN: 2474-1264


  15 in total

1.  Topical Aqueous Suppression and Closure of Idiopathic Full-Thickness Macular Holes.

Authors:  Daniel Su; Anthony Obeid; Jason Hsu
Journal:  Ophthalmic Surg Lasers Imaging Retina       Date:  2019-02-01       Impact factor: 1.300

2.  ATYPICAL MACULAR HOLES.

Authors:  Devesh Kumawat; Pradeep Venkatesh; Anand S Brar; Pranita Sahay; Vinod Kumar; Parijat Chandra; Rohan Chawla
Journal:  Retina       Date:  2019-07       Impact factor: 4.256

3.  EVEREST study: efficacy and safety of verteporfin photodynamic therapy in combination with ranibizumab or alone versus ranibizumab monotherapy in patients with symptomatic macular polypoidal choroidal vasculopathy.

Authors:  Adrian Koh; Won Ki Lee; Lee-Jen Chen; Shih-Jen Chen; Yehia Hashad; Hakyoung Kim; Timothy Y Lai; Stefan Pilz; Paisan Ruamviboonsuk; Erika Tokaji; Annemarie Weisberger; Tock H Lim
Journal:  Retina       Date:  2012-09       Impact factor: 4.256

4.  Macular hole closure following anti-vascular endothelial growth factor injection in an eye with myopic choroidal neovascularization.

Authors:  Cheolmin Yun; Seong-Woo Kim; Kuhl Huh; Jaeryung Oh
Journal:  Int J Ophthalmol       Date:  2016-09-18       Impact factor: 1.779

5.  Idiopathic polypoidal choroidal vasculopathy (IPCV).

Authors:  L A Yannuzzi; J Sorenson; R F Spaide; B Lipson
Journal:  Retina       Date:  1990       Impact factor: 4.256

6.  RESOLUTION OF A MACULAR HOLE COMPLICATING A PSEUDOPHAKIC MACULAR EDEMA WITH NONSURGICAL TREATMENT.

Authors:  Delphine Lam; Mayer Srour; Oudy Semoun; Julien Tilleul; Eric H Souied
Journal:  Retin Cases Brief Rep       Date:  2018 Spring

Review 7.  Polypoidal Choroidal Vasculopathy: Definition, Pathogenesis, Diagnosis, and Management.

Authors:  Chui Ming Gemmy Cheung; Timothy Y Y Lai; Paisan Ruamviboonsuk; Shih-Jen Chen; Youxin Chen; K Bailey Freund; Fomi Gomi; Adrian H Koh; Won-Ki Lee; Tien Yin Wong
Journal:  Ophthalmology       Date:  2018-01-10       Impact factor: 12.079

8.  Efficacy and Safety of Ranibizumab With or Without Verteporfin Photodynamic Therapy for Polypoidal Choroidal Vasculopathy: A Randomized Clinical Trial.

Authors:  Adrian Koh; Timothy Y Y Lai; Kanji Takahashi; Tien Y Wong; Lee-Jen Chen; Paisan Ruamviboonsuk; Colin S Tan; Chrystel Feller; Philippe Margaron; Tock H Lim; Won Ki Lee
Journal:  JAMA Ophthalmol       Date:  2017-11-01       Impact factor: 7.389

9.  Macular Hole Secondary to Polypoidal Choroidal Vasculopathy.

Authors:  Prabu Baskaran; Utsab Pan
Journal:  Middle East Afr J Ophthalmol       Date:  2017 Jul-Sep

10.  Case report of a secondary macular hole closure after intravitreal bevacizumab therapy in a patient with retinal pigment epithelial detachment.

Authors:  Marcus Werner Storch; Hans Hoerauf
Journal:  Indian J Ophthalmol       Date:  2017-07       Impact factor: 1.848

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  1 in total

1.  Simultaneous development of full-thickness macular hole and neovascular age-related macular degeneration.

Authors:  Shuichiro Aoki; Hiroko Imaizumi
Journal:  Am J Ophthalmol Case Rep       Date:  2022-01-22
  1 in total

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