| Literature DB >> 34108839 |
Abstract
The pandemic of 2019 has led to an enormous interest in all aspects of modeling and simulation of infectious diseases. One central issue is the redesign and deployment of ventilation systems to mitigate the transmission of infectious diseases, produced by respiratory emissions such as coughs. This work seeks to develop a combined Digital-Twin and Machine-Learning framework to optimize ventilation systems by building on rapidly computable respiratory emission models developed in Zohdi (Comput Mech 64:1025-1034, 2020). This framework ascertains the placement and flow rates of multiple ventilation units, in order to optimally sequester particles released from respiratory emissions such as coughs, sneezes, etc. Numerical examples are provided to illustrate the framework. © CIMNE, Barcelona, Spain 2021.Entities:
Year: 2021 PMID: 34108839 PMCID: PMC8179093 DOI: 10.1007/s11831-021-09609-3
Source DB: PubMed Journal: Arch Comput Methods Eng ISSN: 1134-3060 Impact factor: 7.302
Fig. 1Left: The model problem studied in this work with hypothetical ventilation unit locations (which will be optimized in this work). Right: Zoom: The release of cough particles-color coded by size (Zohdi [1])
Fig. 2Cough simulation (from a starting height of 2 meters, for ): successive frames indicating the spread of particles. a Large particles travel far and settle quickly and b Small particles do not travel far and settle slowly (Zohdi [1])
Fig. 3Flow patterns with the model. Left: flow velocity magnitude. Right: flow velocity magnitude with streamlines
Fig. 4The basic action of a MLA/GA-Machine Learning Algorithm/Genetic Algorithm. Zohdi [45–47, 39]
Fig. 5Optimization for successively longer time limits of and 2.5 s. Shown is the cost function values (the fraction of particles not trapped) at the end of each generation. The red plot is the cost function associated with the best performing gene and the green function is the average cost function of the entire population. Successively allowing longer simulation times allows the vents to trap more particles
The top system parameter performers () and the corresponding cost function for various overall time limits
| 0.175 | 0.514 | 2.194 | 2.661 | 0.781 | 3.419 | 2.411 | 1.369 | 2.368 | 0.245 | 0.671 | 2.057 | 0.689 | 1.485 | 0.365 | |||
| 2.000 | 0.728 | 2.184 | 2.712 | 0.746 | 3.426 | 2.383 | 1.275 | 2.434 | 0.228 | 0.731 | 2.018 | 0.657 | 1.485 | 0.125 | |||
| 2.225 | 0.514 | 2.343 | 2.931 | 0.765 | 3.307 | 2.429 | 1.205 | 2.466 | 0.228 | 0.736 | 2.057 | 0.669 | 1.494 | 0.025 | |||
| 2.500 | 0.491 | 2.219 | 2.800 | 0.832 | 3.296 | 2.488 | 1.345 | 2.343 | 0.233 | 0.722 | 2.039 | 0.656 | 1.482 | 0.000 |