Literature DB >> 3410832

S-adenosylhomocysteine metabolism in Streptomyces flocculus.

M K Speedie1, J J Zulty, P Brothers.   

Abstract

S-Adenosylhomocysteine metabolism was studied in cell extracts of streptonigrin-producing Streptomyces flocculus. The major route of metabolism was found to be deamination to form S-inosylhomocysteine. The metabolite was purified by high-performance liquid chromatography and identified by its UV and nuclear magnetic resonance spectra and by its chemical degradation to hypoxanthine.

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Year:  1988        PMID： 3410832      PMCID： PMC211453          DOI： 10.1128/jb.170.9.4376-4378.1988

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  12 in total

1.  Potential inhibitor of S-adenosylmethionine-dependent methyltransferases. 2. Modification of the base portion of S-adenosylhomocysteine.

Authors:  R T Borchardt; J A Huber; Y S Wu
Journal:  J Med Chem       Date:  1974-08       Impact factor: 7.446

2.  Studies on S-adenosylhomocysteine inhibition of histamine transmethylation in brain.

Authors:  M Baudry; F Chast; J C Schwartz
Journal:  J Neurochem       Date:  1973-01       Impact factor: 5.372

3.  Inhibition of catechol-O-methyltransferase by S-adenosylhomocysteine and S-adenosylhomocysteine sulfoxide, a potential transition-state analog.

Authors:  J K Coward; M D'Urso-Scott; W D Sweet
Journal:  Biochem Pharmacol       Date:  1972-04-15       Impact factor: 5.858

4.  The action of adenosine deaminase on S-adenosylhomocysteine and related compounds.

Authors:  F Schlenk; C R Zydek
Journal:  Biochem Biophys Res Commun       Date:  1968-05-10       Impact factor: 3.575

Review 5.  Pharmacological and biochemical aspects of S-adenosylhomocysteine and S-adenosylhomocysteine hydrolase.

Authors:  P M Ueland
Journal:  Pharmacol Rev       Date:  1982-09       Impact factor: 25.468

6.  S-adenosylhomocysteine metabolism in various species.

Authors:  R D Walker; J A Duerre
Journal:  Can J Biochem       Date:  1975-03

7.  Occurrence of S-adenosylhomocysteine hydrolase in prokaryote cells. Characterization of the enzyme from Alcaligenes faecalis and role of the enzyme in the activated methyl cycle.

Authors:  S Shimizu; S Shiozaki; T Ohshiro; H Yamada
Journal:  Eur J Biochem       Date:  1984-06-01

8.  A tryptophan C-methyltransferase involved in streptonigrin biosynthesis in Streptomyces flocculus.

Authors:  D L Hartley; M K Speedie
Journal:  Biochem J       Date:  1984-05-15       Impact factor: 3.857

9.  Analysis of S-adenosylmethionine and related sulfur metabolites in animal tissues.

Authors:  G A Miura; J R Santangelo; R K Gordon; P K Chiang
Journal:  Anal Biochem       Date:  1984-08-15       Impact factor: 3.365
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  5 in total

1.  Purification and characterization of S-adenosylhomocysteine deaminase from streptonigrin-producing Streptomyces flocculus.

Authors:  J J Zulty; M K Speedie
Journal:  J Bacteriol       Date:  1989-12       Impact factor: 3.490

2.  Identification of a new class of adenosine deaminase from Helicobacter pylori with homologs among diverse taxa.

Authors:  Erica F Miller; Robert J Maier
Journal:  J Bacteriol       Date:  2013-07-12       Impact factor: 3.490

3.  Identification of a 5'-deoxyadenosine deaminase in Methanocaldococcus jannaschii and its possible role in recycling the radical S-adenosylmethionine enzyme reaction product 5'-deoxyadenosine.

Authors:  Danielle Miller; Kaitlin O'Brien; Huimin Xu; Robert H White
Journal:  J Bacteriol       Date:  2013-12-27       Impact factor: 3.490

4.  Structure-based activity prediction for an enzyme of unknown function.

Authors:  Johannes C Hermann; Ricardo Marti-Arbona; Alexander A Fedorov; Elena Fedorov; Steven C Almo; Brian K Shoichet; Frank M Raushel
Journal:  Nature       Date:  2007-07-01       Impact factor: 49.962

5.  A bicyclic S-adenosylmethionine regeneration system applicable with different nucleosides or nucleotides as cofactor building blocks.

Authors:  Désirée Popadić; Dipali Mhaindarkar; Mike H N Dang Thai; Helen C Hailes; Silja Mordhorst; Jennifer N Andexer
Journal:  RSC Chem Biol       Date:  2021-03-22
  5 in total

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