Literature DB >> 3410460

A noninvasive method for determination of the sex and karyotype of the fetus from the maternal blood.

A Selypes1, R Lorencz.   

Abstract

The noninvasive method presented, using an "air culturing" technique, is capable of enriching for fetal cells in lymphocyte cultures of maternal blood. Through a combination of Y-body fluorescence and chromosomal heteromorphisms in the maternal blood, the fetal cells can be detected and used for the prenatal diagnosis of chromosomal abnormalities and the sex of the fetus in both the first and the second halves of pregnancy.

Entities:  

Mesh：

Year:  1988        PMID： 3410460     DOI： 10.1007/bf00282176

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  10 in total

1.  A simple technique for demonstrating centromeric heterochromatin.

Authors:  A T Sumner
Journal:  Exp Cell Res       Date:  1972-11       Impact factor: 3.905

2.  Identification of human chromosomes by DNA-binding fluorescent agents.

Authors:  T Caspersson; L Zech; C Johansson; E J Modest
Journal:  Chromosoma       Date:  1970       Impact factor: 4.316

3.  Practical and theoretical implications of fetal-maternal lymphocyte transfer.

Authors:  J Walknowska; F A Conte; M M Grumbach
Journal:  Lancet       Date:  1969-06-07       Impact factor: 79.321

4.  The possibility of detecting fetal lymphocytes in the maternal blood of the domestic pig, Sus scrofa.

Authors:  Z Rudek; L Kwiatkowska
Journal:  Cytogenet Cell Genet       Date:  1983

5.  Fetal cells in the maternal circulation: detection by direct AFP-immunofluorescence.

Authors:  A Kulozik; I H Pawlowitzki
Journal:  Hum Genet       Date:  1982       Impact factor: 4.132

Review 6.  Fetal cells from maternal blood: their selection and prospects for use in prenatal diagnosis.

Authors:  D R Parks; L A Herzenberg
Journal:  Methods Cell Biol       Date:  1982       Impact factor: 1.441

7.  Quantitative analysis of high-resolution trypsin-giemsa bands on human prometaphase chromosomes.

Authors:  U Francke; N Oliver
Journal:  Hum Genet       Date:  1978-12-18       Impact factor: 4.132

8.  Fetal cells in the blood of pregnant mothers.

Authors:  J Schroder
Journal:  J Med Genet       Date:  1981-08       Impact factor: 6.318

9.  Chromosome break points in clonal and nonclonal chromosome changes in human chronic lymphocytic leukemia.

Authors:  K Autio; J Schröder
Journal:  Hereditas       Date:  1982       Impact factor: 3.271

10.  Trophoblast cells in peripheral blood from pregnant women.

Authors:  A E Covone; D Mutton; P M Johnson; M Adinolfi
Journal:  Lancet       Date:  1984-10-13       Impact factor: 79.321
  10 in total
  5 in total

Review 1.  Prenatal diagnosis of enzyme defects--an update.

Authors:  B Winchester; E Young
Journal:  Arch Dis Child       Date:  1991-04       Impact factor: 3.791

2.  X-chromatin fluorescence in maternal blood.

Authors:  A Selypes; R Lorencz; S Takács
Journal:  Hum Genet       Date:  1989-06       Impact factor: 4.132

Review 3.  Non-invasive prenatal diagnosis using fetal cells in maternal blood.

Authors:  Y M Lo
Journal:  J Clin Pathol       Date:  1994-12       Impact factor: 3.411

4.  Specific amplification of the ZFY gene to screen sex in man.

Authors:  C Ebensperger; R Studer; J T Epplen
Journal:  Hum Genet       Date:  1989-06       Impact factor: 4.132

5.  Failure to document fetal cells in maternal circulation using the Selypes-Lorencz "air-culture" cytogenetic technique.

Authors:  M Youssef; L P Shulman; A T Tharapel; J L Simpson; S Elias
Journal:  Hum Genet       Date:  1990-06       Impact factor: 4.132
  5 in total

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