Literature DB >> 3410154

Evaluation of a breath operated powder inhaler.

G M Pover1, C G Langdon, S R Jones, C Fidler.   

Abstract

A randomized, double-blind, double-dummy crossover study on 42 asthmatics was carried out to compare the single dose effects of salbutamol administered from the widely used metered dose inhaler and a breath operated system (Diskhaler). The bronchodilator response (change in forced expiratory volume in the first second) was almost identical for the two systems. The Diskhaler system however, since it is breath operated, obviates the need for hand-breath coordination.

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Year:  1988        PMID: 3410154     DOI: 10.1177/030006058801600306

Source DB:  PubMed          Journal:  J Int Med Res        ISSN: 0300-0605            Impact factor:   1.671


  5 in total

1.  A double-blind comparison of the bronchodilatory effect of cumulative doses of salbutamol from Diskus (Accuhaler) and Turbuhaler.

Authors:  Per M Gustafsson
Journal:  Eur J Clin Pharmacol       Date:  2002-02       Impact factor: 2.953

2.  Systematic review of clinical effectiveness of pressurised metered dose inhalers versus other hand held inhaler devices for delivering beta (2 )agonists bronchodilators in asthma.

Authors:  F S Ram; J Wright; D Brocklebank; J E White
Journal:  BMJ       Date:  2001-10-20

Review 3.  Standards for bioequivalence of inhaled products.

Authors:  H Chrystyn
Journal:  Clin Pharmacokinet       Date:  1994-01       Impact factor: 6.447

Review 4.  Salbutamol in the 1980s. A reappraisal of its clinical efficacy.

Authors:  A H Price; S P Clissold
Journal:  Drugs       Date:  1989-07       Impact factor: 9.546

Review 5.  Review of therapeutically equivalent alternatives to short acting beta(2) adrenoceptor agonists delivered via chlorofluorocarbon-containing inhalers.

Authors:  D A Hughes; A Woodcock; T Walley
Journal:  Thorax       Date:  1999-12       Impact factor: 9.139

  5 in total

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