Literature DB >> 34097495

Diversity of Sequence Types and Impact of Fitness Cost among Carbapenem-Resistant Acinetobacter baumannii Isolates from Tripoli, Libya.

Antoine G Abou Fayad1,2,3, Louis-Patrick Haraoui4, Ahmad Sleiman1,2,3, Mohamad Jaafar1,2,3, Abdulaziz Zorgani5, Ghassan M Matar1,2,3, Paul G Higgins6,7.   

Abstract

We investigated the molecular epidemiology of 21 carbapenem-resistant Acinetobacter baumannii isolates from Libya and assessed their relative fitness. Core genome multilocus sequence typing (MLST) revealed five interhospital transmission clusters. Three clusters were associated with the international clones (IC) IC1, IC2, and IC7. Carbapenem-resistance was associated with blaOXA-23, blaGES-11, or blaNDM-1. Compared to that of A. baumannii DSM 30008, the doubling time was similar over 10 h, but after 16 h, half the isolates grew to higher densities, suggesting a fitness advantage.

Entities:  

Keywords:  Acinetobacter baumannii; antimicrobial resistance; carbapenems; fitness cost

Mesh：

Substances：

Year:  2021        PMID： 34097495      PMCID： PMC8373249          DOI： 10.1128/AAC.00277-21

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  15 in total

1.  Identification of an epidemic strain of Acinetobacter baumannii using electrophoretic typing methods.

Authors:  G M Matar; E Gay; R C Cooksey; J A Elliott; W M Heneine; M M Uwaydah; R M Matossian; F C Tenover
Journal:  Eur J Epidemiol       Date:  1992-01       Impact factor: 8.082

2.  Emergence of Carbapenem-Resistant Pseudomonas aeruginosa and Acinetobacter baumannii Clinical Isolates Collected from Some Libyan Hospitals.

Authors:  Najla Mathlouthi; Zaynab Areig; Charbel Al Bayssari; Sofiane Bakour; Allaaeddin Ali El Salabi; Salha Ben Gwierif; Abdulaziz A Zorgani; Karim Ben Slama; Chedly Chouchani; Jean-Marc Rolain
Journal:  Microb Drug Resist       Date:  2015-01-14       Impact factor: 3.431

3.  Comparison of Acinetobacter baumannii isolates from the United Kingdom and the United States that were associated with repatriated casualties of the Iraq conflict.

Authors:  Jane F Turton; Mary E Kaufmann; Martin J Gill; Rachel Pike; Paul T Scott; Joel Fishbain; David Craft; Gregory Deye; Scott Riddell; Luther E Lindler; Tyrone L Pitt
Journal:  J Clin Microbiol       Date:  2006-07       Impact factor: 5.948

4.  Impact of blaNDM-1 on fitness and pathogenicity of Escherichia coli and Klebsiella pneumoniae.

Authors:  Stephan Göttig; Sara Riedel-Christ; Ahmad Saleh; Volkhard A J Kempf; Axel Hamprecht
Journal:  Int J Antimicrob Agents       Date:  2016-04-26       Impact factor: 5.283

5.  A PCR-based method to differentiate between Acinetobacter baumannii and Acinetobacter genomic species 13TU.

Authors:  P G Higgins; H Wisplinghoff; O Krut; H Seifert
Journal:  Clin Microbiol Infect       Date:  2007-09-10       Impact factor: 8.067

6.  Occupational transmission of Acinetobacter baumannii from a United States serviceman wounded in Iraq to a health care worker.

Authors:  Timothy J Whitman; Sonia S Qasba; Joseph G Timpone; Britta S Babel; Matthew R Kasper; Judith F English; John W Sanders; Kristine M Hujer; Andrea M Hujer; Andrea Endimiani; Mark W Eshoo; Robert A Bonomo
Journal:  Clin Infect Dis       Date:  2008-08-15       Impact factor: 9.079

7.  Early detection of metallo-β-lactamase NDM-1- and OXA-23 carbapenemase-producing Acinetobacter baumannii in Libyan hospitals.

Authors:  Najla Mathlouthi; Allaaeddin Ali El Salabi; Mariem Ben Jomàa-Jemili; Sofiane Bakour; Charbel Al-Bayssari; Abdulaziz A Zorgani; Abdulmajeed Kraiema; Omar Elahmer; Liliane Okdah; Jean-Marc Rolain; Chedly Chouchani
Journal:  Int J Antimicrob Agents       Date:  2016-04-25       Impact factor: 5.283

Review 8.  Mechanisms of Antimicrobial Resistance in ESKAPE Pathogens.

Authors:  Sirijan Santajit; Nitaya Indrawattana
Journal:  Biomed Res Int       Date:  2016-05-05       Impact factor: 3.411

9.  Development and evaluation of a core genome multilocus typing scheme for whole-genome sequence-based typing of Acinetobacter baumannii.

Authors:  Paul G Higgins; Karola Prior; Dag Harmsen; Harald Seifert
Journal:  PLoS One       Date:  2017-06-08       Impact factor: 3.240

10.  The Effect of Colistin Resistance-Associated Mutations on the Fitness of Acinetobacter baumannii.

Authors:  Xinli Mu; Nanfei Wang; Xi Li; Keren Shi; Zhihui Zhou; Yunsong Yu; Xiaoting Hua
Journal:  Front Microbiol       Date:  2016-11-01       Impact factor: 5.640
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