The Application of Omics Technologies in the Research of Neurotoxicology.

Omics technologies offer unprecedented perspectives for the systematic research of complex organisms. Especially, the comprehensive omics provide powerful tools for exploring extensive perception of the biochemical and/or physiological effects of the cells perturbed by poisons through systemic investigation on the different spatiotemporal expression profiles of transcriptomic expression profiling, expressed proteins and metabolites simultaneously by high-throughput and high-sensitivity technology. Therefore, it has been attracted extensive attention in neurotoxicology. During the recent years, the domain of neurotoxicology has progressively assimilated various emerging omics applications, which mainly include transcriptomics, proteomics, and metabolomics, to investigate the molecular mechanisms and potential molecular biomarkers of phenotypic modifications of organisms subjected to poisons or stress factors.