Literature DB >> 34097260

Methods to Assay the Behavior of Drosophila melanogaster for Toxicity Study.

Guiran Xiao1.   

Abstract

Drosophila melanogaster, the fruit fly, has been widely used in biological investigation as an invertebrate alternative to mammals for its various advantages compared to other model organisms, which include short life cycle, easy handling, high prolificacy, and great availability of substantial genetic information. The behavior of Drosophila melanogaster is closely related to its growth, which can reflect the physiological conditions of Drosophila. We have optimized simple and robust behavioral assays for determining the larvae survival, adult climbing ability (mobility assay), reproductive behavior, and lifespan of Drosophila. In this chapter, we present the step-by-step detailed method for studying Drosophila behavior.

Entities:  

Keywords:  Climbing ability; Drosophila melanogaster; Lifespan; Reproductive; Survival

Year:  2021        PMID： 34097260     DOI： 10.1007/978-1-0716-1514-0_4

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  14 in total

1.  A simple assay to study social behavior in Drosophila: measurement of social space within a group.

Authors:  A F Simon; M-T Chou; E D Salazar; T Nicholson; N Saini; S Metchev; D E Krantz
Journal:  Genes Brain Behav       Date:  2011-11-23       Impact factor: 3.449

2.  Oxidative stress caused by lead (Pb) induces iron deficiency in Drosophila melanogaster.

Authors:  Zhi-Hua Liu; Jin Shang; Lailai Yan; Tian Wei; Ling Xiang; Hui-Li Wang; Jigui Cheng; Guiran Xiao
Journal:  Chemosphere       Date:  2019-11-20       Impact factor: 7.086

3.  Pantothenate kinase-associated neurodegeneration: insights from a Drosophila model.

Authors:  Zhihao Wu; Chenghua Li; Shan Lv; Bing Zhou
Journal:  Hum Mol Genet       Date:  2009-07-13       Impact factor: 6.150

4.  Huntington disease arises from a combinatory toxicity of polyglutamine and copper binding.

Authors:  Guiran Xiao; Qiangwang Fan; Xiaoxi Wang; Bing Zhou
Journal:  Proc Natl Acad Sci U S A       Date:  2013-08-26       Impact factor: 11.205

5.  Transferrin1 modulates rotenone-induced Parkinson's disease through affecting iron homeostasis in Drosophila melanogaster.

Authors:  Jinsong Xue; Hui-Li Wang; Guiran Xiao
Journal:  Biochem Biophys Res Commun       Date:  2020-08-14       Impact factor: 3.575

6.  Developmental arrest in Drosophila melanogaster caused by mitochondrial DNA replication defects cannot be rescued by the alternative oxidase.

Authors:  Ana Paula C Rodrigues; André F Camargo; Ana Andjelković; Howard T Jacobs; Marcos T Oliveira
Journal:  Sci Rep       Date:  2018-07-18       Impact factor: 4.379

7.  Interaction between Ras(V12) and scribbled clones induces tumour growth and invasion.

Authors:  Ming Wu; José Carlos Pastor-Pareja; Tian Xu
Journal:  Nature       Date:  2010-01-13       Impact factor: 49.962

8.  Genetic inhibition of solute-linked carrier 39 family transporter 1 ameliorates aβ pathology in a Drosophila model of Alzheimer's disease.

Authors:  Minglin Lang; Lei Wang; Qiangwang Fan; Guiran Xiao; Xiaoxi Wang; Yi Zhong; Bing Zhou
Journal:  PLoS Genet       Date:  2012-04-26       Impact factor: 5.917

9.  The metal transporter ZIP13 supplies iron into the secretory pathway in Drosophila melanogaster.

Authors:  Guiran Xiao; Zhihui Wan; Qiangwang Fan; Xiaona Tang; Bing Zhou
Journal:  Elife       Date:  2014-07-08       Impact factor: 8.140

10.  Larval mannitol diets increase mortality, prolong development and decrease adult body sizes in fruit flies (Drosophila melanogaster).

Authors:  Meghan Barrett; Katherine Fiocca; Edward A Waddell; Cheyenne McNair; Sean O'Donnell; Daniel R Marenda
Journal:  Biol Open       Date:  2020-01-02       Impact factor: 2.422
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