Literature DB >> 34097089

[Disease burden of borderline personality disorder: cost of illness, somatic comorbidity and mortality].

Frank Jacobi1, Raphaela Grafiadeli2, Hannah Volkmann2, Isabella Schneider3.   

Abstract

BACKGROUND: Severe mental illnesses (SMI) are characterized by high psychosocial impairment as well as by increased somatic morbidity and mortality. The term SMI commonly includes psychotic, bipolar and severe unipolar depressive disorders but borderline personality disorder (BPD) also shows severe sequelae of the disease.
MATERIAL AND METHODS: Published reviews and studies since 2010 examining disease burden of BPD, in terms of direct and indirect costs of illness, somatic comorbidity, and mortality were included. Furthermore, administrative data (clinically recorded billing data in Germany), comorbidity and mortality from a comprehensive analysis (n > 59 million, age ≥ 18 years) are reported.
RESULTS: International studies reveal an increased disease burden, comorbidity, and mortality for BPD. In Germany BPD (administrative 1‑year prevalence 0.34%) is associated with increased rates of somatic sequelae of trauma, hepatitis, HIV, COPD, asthma, and obesity. The estimated reduced life expectancy is 5.0-9.3 years of life lost (depending on age and sex). DISCUSSION: The burden of disease in BPD is clearly increased (cost of illness, somatic comorbidity and mortality). The increased mortality can mainly be explained by deaths as a consequence of poor physical health and associated BPD-related health behavior and only to a lesser degree by suicide. These results highlight the importance of classifying BPD as an SMI and the necessity to provide not only psychotherapeutic and psychiatric but also adequate somatic prevention and treatment. Individual improvement of everyday care as well as establishing new interdisciplinary and multiprofessional services could enhance health equality for people with BPD.

Entities:  

Keywords:  Borderline personality disorder; Physical health; Severe mental disorders; Somatic prevention; Suicide

Mesh:

Year:  2021        PMID: 34097089     DOI: 10.1007/s00115-021-01139-4

Source DB:  PubMed          Journal:  Nervenarzt        ISSN: 0028-2804            Impact factor:   1.214


  45 in total

1.  Comorbidity and associated severity of borderline personality disorder and physical health conditions in a nationally representative sample.

Authors:  Renée El-Gabalawy; Laurence Y Katz; Jitender Sareen
Journal:  Psychosom Med       Date:  2010-05-27       Impact factor: 4.312

2.  Prevalence, Mortality, and Health Care Use among Patients with Cluster B Personality Disorders Clinically Diagnosed in Quebec: A Provincial Cohort Study, 2001-2012.

Authors:  Lionel Cailhol; Éric Pelletier; Louis Rochette; Lise Laporte; Pierre David; Évens Villeneuve; Joel Paris; Alain Lesage
Journal:  Can J Psychiatry       Date:  2017-04-12       Impact factor: 4.356

Review 3.  Borderline Personality Disorder in Patients With Medical Illness: A Review of Assessment, Prevalence, and Treatment Options.

Authors:  Stephan Doering
Journal:  Psychosom Med       Date:  2019-09       Impact factor: 4.312

4.  A meta-analysis of treatment as usual for borderline personality disorder.

Authors:  Ellen F Finch; Evan A Iliakis; Sara R Masland; Lois W Choi-Kain
Journal:  Personal Disord       Date:  2019-08-15

5.  Coroners' investigations of suicide in Australia: The hidden toll of borderline personality disorder.

Authors:  Jillian H Broadbear; Jeremy Dwyer; Lyndal Bugeja; Sathya Rao
Journal:  J Psychiatr Res       Date:  2020-07-29       Impact factor: 4.791

6.  Health care costs of borderline personality disorder and matched controls with major depressive disorder: a comparative study based on anonymized claims data.

Authors:  Katharina Bode; Rolf Vogel; Jochen Walker; Christoph Kröger
Journal:  Eur J Health Econ       Date:  2016-12-18

7.  Risks of all-cause and suicide mortality in mental disorders: a meta-review.

Authors:  Edward Chesney; Guy M Goodwin; Seena Fazel
Journal:  World Psychiatry       Date:  2014-06       Impact factor: 49.548

Review 8.  The complexities of the borderline patient: how much more complex when considering physical health?

Authors:  David J Castle
Journal:  Australas Psychiatry       Date:  2019-05-09       Impact factor: 1.369

Review 9.  A systematic review of economic evaluations of treatments for borderline personality disorder.

Authors:  Christian Brettschneider; Steffi Riedel-Heller; Hans-Helmut König
Journal:  PLoS One       Date:  2014-09-29       Impact factor: 3.240

10.  Excess cause-specific mortality in out-patients with personality disorder.

Authors:  Charlotte Björkenstam; Emma Björkenstam; Bengt Gerdin; Lisa Ekselius
Journal:  BJPsych Open       Date:  2015-08-20
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.