| Literature DB >> 34094786 |
Anusha Bapatla1, Ameena Syed1, Abu Fazal Shaik Mohammed1, Cortney V Jones2, Rana Ismail1.
Abstract
Gastric neuroendocrine tumors (GNETs) are rare and subdivided into type I, type II, and type III. Types I and II are gastrin-dependent and are usually benign, whereas type III is gastrin-independent and more aggressive. Type I accounts for 70-80% of all GNETs. Most of them are asymptomatic and incidentally detected on endoscopy. It can sometimes present with iron and B12 deficiency, dyspepsia, and less commonly with an upper GI bleed. We present a case of type I GNET who came to the hospital with melena and esophagogastroduodenoscopy (EGD) showing a 3-cm bleeding polyp and histopathology revealing a well-differentiated neuroendocrine tumor with angioinvasion.Entities:
Keywords: chronic atrophic gastritis; enterochromaffin like cells; gastric neuroendocrine tumors; pernicious anemia; type 1 gastric neuroendocrine tumors
Year: 2021 PMID: 34094786 PMCID: PMC8172005 DOI: 10.7759/cureus.15343
Source DB: PubMed Journal: Cureus ISSN: 2168-8184