Literature DB >> 34093967

Molecular prevalence of eight different sexually transmitted infections in a Lebanese major tertiary care center: impact on public health.

Nancy El Beayni1, Lina Hamad2, Christine Nakad1, Sose Keleshian1, Soha N Yazbek2, Rami Mahfouz1.   

Abstract

BACKGROUND: Sexually transmitted diseases (STD) are caused by a variety of pathogens transmitted by sexual activity. Untreated infections can cause major complications with a substantial high cost on health sector. With the development of molecular techniques, STD screening became easier with a high sensitivity and specificity.
OBJECTIVES: In Lebanon, official data regarding STD trends are scarce. This study elucidates the STD molecular profile at a tertiary care center, American University of Beirut Medical Center (AUBMC), its distribution among gender and age groups, with a comparison to international studies.
METHODS: A retrospective data analysis was conducted on all STD panels performed at AUBMC from January 2017 till December 2019 to determine the molecular prevalence of eight different sexually transmitted organisms.
RESULTS: Our samples belonged to 248 females (41.5%) and 349 males (58.5%). Only 53.5% of the samples tested positive for one or more organisms. Ureaplasma urealyticum/parvum was found to be the most common pathogen (49.3%), followed by Gardenerella vaginalis (33.5%), Chlamydia trachomatis (5.36%), Mycoplasma genitalium (5.16%), Neisseria gonorrhea (2.5%), Herpes simplex virus (2.5%), and Trichomonas vaginalis (1.39%). Age was distributed between 5 and 80 years old. Regarding the pathogen's distribution among gender, Ureaplasma urealyticum/parvum, Herpes simplex virus, and Gardenerella vaginalis were more common in females, the rest was more detected in males.
CONCLUSION: Data will be of great importance for clinicians, in terms of diagnosis and treatment. It will help adopting an evidence based STI control programs in Lebanon, and it is essential for future larger studies and sexual health awareness programs. IJMEG
Copyright © 2021.

Entities:  

Keywords:  Lebanon; STD panel; STI; molecular prevalence; multiplex PCR

Year:  2021        PMID: 34093967      PMCID: PMC8166729     

Source DB:  PubMed          Journal:  Int J Mol Epidemiol Genet        ISSN: 1948-1756


  38 in total

1.  Prevalence of cervical colonization by Ureaplasma parvum, Ureaplasma urealyticum, Mycoplasma hominis and Mycoplasma genitalium in childbearing age women by a commercially available multiplex real-time PCR: An Italian observational multicentre study.

Authors:  Christian Leli; Antonella Mencacci; Maria Agnese Latino; Pierangelo Clerici; Mario Rassu; Stefano Perito; Roberto Castronari; Eleonora Pistoni; Eugenio Luciano; Daniela De Maria; Cristina Morazzoni; Michela Pascarella; Silvia Bozza; Alessandra Sensini
Journal:  J Microbiol Immunol Infect       Date:  2017-06-28       Impact factor: 4.399

2.  Modelling the cost effectiveness of rapid point of care diagnostic tests for the control of HIV and other sexually transmitted infections among female sex workers.

Authors:  P Vickerman; C Watts; R W Peeling; D Mabey; M Alary
Journal:  Sex Transm Infect       Date:  2006-10       Impact factor: 3.519

3.  The National Network of Sexually Transmitted Disease Clinical Prevention Training Centers Turns 40-A Look Back, a Look Ahead.

Authors:  Bradley P Stoner; Jami Fraze; Cornelis A Rietmeijer; Janine Dyer; Alice Gandelman; Edward W Hook; Christine Johnston; Natalie M Neu; Anne M Rompalo; Gail Bolan
Journal:  Sex Transm Dis       Date:  2019-08       Impact factor: 2.830

4.  Performance of Anyplex™ II multiplex real-time PCR for the diagnosis of seven sexually transmitted infections: comparison with currently available methods.

Authors:  Hyun-Sop Choe; Dong Sup Lee; Seung-Ju Lee; Sung-Hoo Hong; Dong Choon Park; Mi-Kyung Lee; Tae-Hyoung Kim; Yong-Hyun Cho
Journal:  Int J Infect Dis       Date:  2013-09-07       Impact factor: 3.623

5.  Implementation of an Sexually Transmitted Disease-Screening Protocol in an Emergency Department: A Quality Improvement Project to Increase STD Screenings in Young Adults Aged 15-29 Years With Urinary Symptoms.

Authors:  Binnara Yoo; Brigit Vangrafeiland
Journal:  Adv Emerg Nurs J       Date:  2018 Oct/Dec

6.  Increasing proportion of herpes simplex virus type 1 as a cause of genital herpes infection in college students.

Authors:  Craig M Roberts; John R Pfister; Scott J Spear
Journal:  Sex Transm Dis       Date:  2003-10       Impact factor: 2.830

7.  A cross-sectional study of Mycoplasma genitalium infection and correlates in women undergoing population-based screening or clinic-based testing for Chlamydia infection in London.

Authors:  H F Svenstrup; S S Dave; C Carder; P Grant; S Morris-Jones; M Kidd; J M Stephenson
Journal:  BMJ Open       Date:  2014-02-06       Impact factor: 2.692

8.  Prevalence and distribution of Gardnerella vaginalis subgroups in women with and without bacterial vaginosis.

Authors:  Migle Janulaitiene; Virginija Paliulyte; Svitrigaile Grinceviciene; Jolita Zakareviciene; Alma Vladisauskiene; Agne Marcinkute; Milda Pleckaityte
Journal:  BMC Infect Dis       Date:  2017-06-05       Impact factor: 3.090

Review 9.  Prevalence of Mycoplasma genitalium in different population groups: systematic review andmeta-analysis.

Authors:  Lukas Baumann; Manuel Cina; Dianne Egli-Gany; Myrofora Goutaki; Florian S Halbeisen; Gian-Reto Lohrer; Hammad Ali; Pippa Scott; Nicola Low
Journal:  Sex Transm Infect       Date:  2018-02-09       Impact factor: 3.519

10.  Genital Chlamydia trachomatis infections in young adults - a school-based bio-behavioural study in urban areas, Poland, 2012 to 2015.

Authors:  Michal Czerwinski; Marta Niedzwiedzka-Stadnik; Anna Zielicka-Hardy; Anna Tomusiak; Malgorzata Sadkowska-Todys; Andrzej Zielinski; Magdalena Strus; Piotr Heczko; Magdalena Rosinska
Journal:  Euro Surveill       Date:  2018-02
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