Literature DB >> 34087086

Drug and alcohol positivity of traumatically injured patients related to COVID-19 stay-at-home orders.

Kirsten N Young1, Eric O Yeates1, Areg Grigorian1,2, Morgan Schellenberg2, Natthida Owattanapanich2, Galinos Barmparas3, Daniel Margulies3, Catherine Juillard4, Kent Garber4, Henry Cryer4, Areti Tillou4, Sigrid Burruss5, Liz Penaloza-Villalobos5, Ann Lin5, Ryan Arthur Figueras5, Megan Brenner6, Christopher Firek7, Todd Costantini8, Jarrett Santorelli8, Terry Curry8, Diane Wintz9, Walter L Biffl10, Kathryn B Schaffer10, Thomas K Duncan11, Casey Barbaro11, Graal Diaz11, Arianne Johnson12, Justine Chinn1, Ariana Naaseh1, Amanda Leung1, Christina Grabar1, Jeffry Nahmias1.   

Abstract

Background: COVID-19 related stay-at-home (SAH) orders created many economic and social stressors, possibly increasing the risk of drug/alcohol abuse in the community and trauma population.
Objectives: Describe changes in alcohol/drug use in traumatically injured patients after SAH orders in California and evaluate demographic or injury pattern changes in alcohol or drug-positive patients.
Methods: A retrospective analysis of 11 trauma centers in Southern California (1/1/2020-6/30/2020) was performed. Blood alcohol concentration, urine toxicology results, demographics, and injury characteristics were collected. Patients were grouped based on injury date - before SAH (PRE-SAH), immediately after SAH (POST-SAH), and a historical comparison (3/19/2019-6/30/2019) (CONTROL) - and compared in separate analyses. Groups were compared using chi-square tests for categorical variables and Mann-Whitney U tests for continuous variables.
Results: 20,448 trauma patients (13,634 male, 6,814 female) were identified across three time-periods. The POST-SAH group had higher rates of any drug (26.2% vs. 21.6% and 24.7%, OR = 1.26 and 1.08, p < .001 and p = .035), amphetamine (10.4% vs. 7.5% and 9.3%, OR = 1.43 and 1.14, p < .001 and p = .023), tetrahydrocannabinol (THC) (13.8% vs. 11.0% and 11.4%, OR = 1.30 and 1.25, p < .001 and p < .001), and 3,4-methylenedioxy methamphetamine (MDMA) (0.8% vs. 0.4% and 0.2%, OR = 2.02 and 4.97, p = .003 and p < .001) positivity compared to PRE-SAH and CONTROL groups. Alcohol concentration and positivity were similar between groups (p > .05).
Conclusion: This Southern California multicenter study demonstrated increased amphetamine, MDMA, and THC positivity in trauma patients after SAH, but no difference in alcohol positivity or blood concentration. Drug prevention strategies should continue to be adapted within and outside of hospitals during a pandemic.

Entities:  

Keywords:  Alcohol; COVID-19; amphetamines; drugs; quarantine; stay-at-home; toxicology; trauma

Year:  2021        PMID: 34087086     DOI: 10.1080/00952990.2021.1904967

Source DB:  PubMed          Journal:  Am J Drug Alcohol Abuse        ISSN: 0095-2990            Impact factor:   3.829


  6 in total

1.  Adolescent Trauma During the COVID Pandemic: Just Like Adults, Children, or Someone Else?

Authors:  Perisa Ruhi-Williams; Eric O Yeates; Areg Grigorian; Morgan Schellenberg; Natthida Owattanapanich; Galinos Barmparas; Daniel Margulies; Catherine Juillard; Kent Garber; Henry Cryer; Areti Tillou; Sigrid Burruss; Liz Penaloza-Villalobos; Ann Lin; Ryan Arthur Figueras; Raul Coimbra; Megan Brenner; Todd Costantini; Jarrett Santorelli; Terry Curry; Diane Wintz; Walter L Biffl; Kathryn B Schaffer; Thomas K Duncan; Casey Barbaro; Graal Diaz; Arianne Johnson; Justine Chinn; Ariana Naaseh; Amanda Leung; Christina Grabar; Jeffry Nahmias
Journal:  Am Surg       Date:  2022-05-18       Impact factor: 1.002

2.  Response to Wyatt et al.'s comment on "Changes in traumatic mechanisms of injury in Southern California related to COVID-19: Penetrating trauma as a second pandemic".

Authors:  Eric O Yeates; Jeffry Nahmias
Journal:  J Trauma Acute Care Surg       Date:  2021-07-01       Impact factor: 3.313

3.  Effects of the COVID-19 pandemic on pediatric trauma in Southern California.

Authors:  Eric O Yeates; Areg Grigorian; Morgan Schellenberg; Natthida Owattanapanich; Galinos Barmparas; Daniel Margulies; Catherine Juillard; Kent Garber; Henry Cryer; Areti Tillou; Sigrid Burruss; Liz Penaloza-Villalobos; Ann Lin; Ryan Arthur Figueras; Raul Coimbra; Megan Brenner; Todd Costantini; Jarrett Santorelli; Terry Curry; Diane Wintz; Walter L Biffl; Kathryn B Schaffer; Thomas K Duncan; Casey Barbaro; Graal Diaz; Arianne Johnson; Justine Chinn; Ariana Naaseh; Amanda Leung; Christina Grabar; Jeffry Nahmias
Journal:  Pediatr Surg Int       Date:  2021-12-01       Impact factor: 1.827

Review 4.  Illicit Substance Use and the COVID-19 Pandemic in the United States: A Scoping Review and Characterization of Research Evidence in Unprecedented Times.

Authors:  Anh Truc Vo; Thomas Patton; Amy Peacock; Sarah Larney; Annick Borquez
Journal:  Int J Environ Res Public Health       Date:  2022-07-21       Impact factor: 4.614

5.  Pre-injury stimulant use in isolated severe traumatic brain injury: effect on outcomes.

Authors:  Dominik Andreas Jakob; Meghan Lewis; Elizabeth Robinson Benjamin; Tobias Haltmeier; Beat Schnüriger; Aristomenis Konstantinos Exadaktylos; Demetrios Demetriades
Journal:  Eur J Trauma Emerg Surg       Date:  2022-09-06       Impact factor: 2.374

6.  The effect of the COVID-19 pandemic on community violence in Connecticut.

Authors:  Kathleen M O'Neill; James Dodington; Marcie Gawel; Kevin Borrup; David S Shapiro; Jonathan Gates; Shea Gregg; Robert D Becher
Journal:  Am J Surg       Date:  2022-10-07       Impact factor: 3.125

  6 in total

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