Emma Johansson1, Magnus Hultin2, Tomi Myrberg3, Jakob Walldén1. 1. Department of Surgical and Perioperative Sciences, Anaesthesiology and Intensive Care Medicine (Sundsvall), Umeå University, Umeå, Sweden. 2. Department of Surgical and Perioperative Sciences, Anaesthesiology and Intensive Care Medicine (Umeå), Umeå University, Umeå, Sweden. 3. Department of Surgical and Perioperative Sciences, Anaesthesiology and Intensive Care Medicine (Sunderbyn), Umeå University, Umeå, Sweden.
Abstract
BACKGROUND: The overall risk of postoperative nausea and vomiting (PONV) after general anaesthesia is reportedly 20%-40%. The first episode of PONV may occur early in the post-anaesthesia care unit (PACU), or later at the ward or after discharge at home in an ambulatory setting. This study aimed to investigate and describe the risk of early PONV in a PACU and we hypothesised that patients- and perioperative factors were associated with early PONV. METHODS: This single-centre retrospective observational study was conducted in a Swedish county hospital from January to June 2017 and included adult patients who underwent surgical procedures under general anaesthesia. Perioperative data were obtained by reviewing the local registry for surgical procedures, medical records, and anaesthesia and postoperative charts. Early PONV was defined as PONV occurring up to four hours postoperatively at the PACU. Any notification in the medical records, perioperative charts, or the registry regarding nausea, vomiting, or PONV treatment was regarded as PONV. Uni- and multivariate analyses were performed for factors associated with early PONV. RESULTS: 2030 patients were included in the study, of which 9.6 % (n=194) experienced early PONV. Factors associated with a high risk of early PONV were suboptimal PONV prophylaxis, need for opioids, female sex, body mass index > 35 kg/m2 , and major surgery and anaesthesia time ≥ 60 minutes. CONCLUSION: We found that every tenth patient under general anaesthesia experienced early PONV. Suboptimal PONV prophylaxis and previously acknowledged risk factors for PONV were associated with early PONV. This article is protected by copyright. All rights reserved.
BACKGROUND: The overall risk of postoperative nausea and vomiting (PONV) after general anaesthesia is reportedly 20%-40%. The first episode of PONV may occur early in the post-anaesthesia care unit (PACU), or later at the ward or after discharge at home in an ambulatory setting. This study aimed to investigate and describe the risk of early PONV in a PACU and we hypothesised that patients- and perioperative factors were associated with early PONV. METHODS: This single-centre retrospective observational study was conducted in a Swedish county hospital from January to June 2017 and included adult patients who underwent surgical procedures under general anaesthesia. Perioperative data were obtained by reviewing the local registry for surgical procedures, medical records, and anaesthesia and postoperative charts. Early PONV was defined as PONV occurring up to four hours postoperatively at the PACU. Any notification in the medical records, perioperative charts, or the registry regarding nausea, vomiting, or PONV treatment was regarded as PONV. Uni- and multivariate analyses were performed for factors associated with early PONV. RESULTS: 2030 patients were included in the study, of which 9.6 % (n=194) experienced early PONV. Factors associated with a high risk of early PONV were suboptimal PONV prophylaxis, need for opioids, female sex, body mass index > 35 kg/m2 , and major surgery and anaesthesia time ≥ 60 minutes. CONCLUSION: We found that every tenth patient under general anaesthesia experienced early PONV. Suboptimal PONV prophylaxis and previously acknowledged risk factors for PONV were associated with early PONV. This article is protected by copyright. All rights reserved.
Entities:
Keywords:
Observational study; Post-anaesthesia care unit; Postoperative nausea and vomiting