Literature DB >> 34084677

Cerebral Venous Thrombosis and Its Clinical Diversity.

Giovana Ennis1, Nelson Domingues1, Joana Silva Marques1, Pedro Ribeiro1, Cristina Andrade1.   

Abstract

Cerebral venous thrombosis (CVT) is a serious medical condition which is difficult to diagnose because of its wide range of clinical presentations. The symptoms can vary from an isolated headache to coma. Here, we present the case of a 76-year-old female patient with a history of immune thrombocytopenic purpura, arterial hypertension, and pulmonary embolism. The diagnosis of CVT was challenging because the initial form of disease presentation mimicked a transient ischemic attack (transient aphasia and right hemiparesis). Therapeutical decisions were also a challenge because, at the time of the diagnosis, the patient was suffering from severe thrombocytopenia (29 × 109/L), which had to be taken into account. After multidisciplinary discussions, therapeutic subcutaneous enoxaparin was started, resulting in a progressive and significant neurological recovery. In presenting this case, our primary goal is to point out that CVT can be difficult to diagnose because of its wide range of clinical presentations. Headache (a symptom that was never present in this case) is the most frequent complaint, occurring in 90% of cases. Following diagnosis, an etiological study is required.
Copyright © 2021, Ennis et al.

Entities:  

Keywords:  cerebral venous infarction; cerebral venous thrombosis; immune thrombocytopenia purpura; stroke; thrombocytopenia

Year:  2021        PMID: 34084677      PMCID: PMC8163355          DOI: 10.7759/cureus.14750

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  10 in total

1.  Dural sinus thrombosis mimicking "capsular warning syndrome".

Authors:  J M Ferro; F Falcao; T P Melo; J G Campos
Journal:  J Neurol       Date:  2000-10       Impact factor: 4.849

Review 2.  Cerebral venous thrombosis: diagnosis and management.

Authors:  M G Bousser
Journal:  J Neurol       Date:  2000-04       Impact factor: 4.849

Review 3.  The American Society of Hematology 2011 evidence-based practice guideline for immune thrombocytopenia.

Authors:  Cindy Neunert; Wendy Lim; Mark Crowther; Alan Cohen; Lawrence Solberg; Mark A Crowther
Journal:  Blood       Date:  2011-02-16       Impact factor: 22.113

4.  Cerebral vein and dural sinus thrombosis in Portugal: 1980-1998.

Authors:  J M Ferro; M Correia; C Pontes; M V Baptista; F Pita
Journal:  Cerebrovasc Dis       Date:  2001       Impact factor: 2.762

Review 5.  How to treat cerebral venous and sinus thrombosis.

Authors:  J M Coutinho; J Stam
Journal:  J Thromb Haemost       Date:  2010-02-09       Impact factor: 5.824

6.  The incidence of cerebral venous thrombosis: a cross-sectional study.

Authors:  Jonathan M Coutinho; Susanna M Zuurbier; Majid Aramideh; Jan Stam
Journal:  Stroke       Date:  2012-09-20       Impact factor: 7.914

7.  Prognosis of cerebral vein and dural sinus thrombosis: results of the International Study on Cerebral Vein and Dural Sinus Thrombosis (ISCVT).

Authors:  José M Ferro; Patrícia Canhão; Jan Stam; Marie-Germaine Bousser; Fernando Barinagarrementeria
Journal:  Stroke       Date:  2004-02-19       Impact factor: 7.914

Review 8.  Cerebral venous and sinus thrombosis.

Authors:  F Masuhr; S Mehraein; K Einhäupl
Journal:  J Neurol       Date:  2004-01       Impact factor: 4.849

9.  Early seizures in cerebral vein and dural sinus thrombosis: risk factors and role of antiepileptics.

Authors:  José M Ferro; Patrícia Canhão; Marie-Germaine Bousser; Jan Stam; Fernando Barinagarrementeria
Journal:  Stroke       Date:  2008-02-28       Impact factor: 7.914

10.  Cerebral Venous Thrombosis after Intravenous Immunoglobulin Therapy in Immune Thrombocytopenic Purpura.

Authors:  Joe James; P V Shiji; Chandni Radhakrishnan
Journal:  Indian J Crit Care Med       Date:  2017-12
  10 in total

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