Literature DB >> 34084242

Parathyroid Adenoma within the Carotid Sheath.

A Chopra1, R Bansal1, N Sharma1, B Kulshreshtha1.   

Abstract

OBJECTIVE: Ectopic parathyroid adenoma is an uncommon cause of primary hyperparathyroidism. Apart from the usually described sites of ectopic parathyroid adenoma, anecdotal case reports of undescended parathyroid adenoma along the carotid artery have been described.
METHODS: We report a rare case of a 4 cm large parathyroid adenoma within the carotid sheath.
RESULTS: A 27-year-old lady presented with severe bony pains, history of height loss, fracture of left shaft femur following trivial trauma and renal calculi. On evaluation she had hypercalcemia with elevated iPTH suggestive of primary hyperparathyroidism. Ultrasound of neck and 99mTc sestamibi SPECT/CT incorrectly localised the lesion as right inferior parathyroid adenoma leading to a failed initial surgery. Later CECT of the neck identified adenoma posterior to right common carotid artery which was confirmed on repeat surgery and the patient was cured.
CONCLUSION: Ectopic parathyroid adenomas are both difficult to localise and are a common cause of failed initial parathyroid surgery. Surgeons should exercise caution while removing a visually normal parathyroid gland. In case of any discordance with the pre-operative localization, a meticulous systematic dissection using the conventional approach should be performed and the possibility of an undescended gland in the carotid sheath should be considered. ©by Acta Endocrinologica Foundation.

Entities:  

Keywords:  carotid sheath; ectopic; parathyroid adenoma; primary hyperparathyroidism

Year:  2020        PMID: 34084242      PMCID: PMC8126382          DOI: 10.4183/aeb.2020.497

Source DB:  PubMed          Journal:  Acta Endocrinol (Buchar)        ISSN: 1841-0987            Impact factor:   0.877


  9 in total

Review 1.  Clinical practice. Primary hyperparathyroidism.

Authors:  Claudio Marcocci; Filomena Cetani
Journal:  N Engl J Med       Date:  2011-12-22       Impact factor: 91.245

2.  Ectopic Parathyroid Adenoma in the Carotid Sheath.

Authors:  Christopher D Sanders; Jared D Kirkland; Ely A Wolin
Journal:  J Nucl Med Technol       Date:  2016-02-04

3.  A case of congenital agenesis of the common carotid artery associated with an ectopic parathyroid adenoma mimicking a carotid body tumor.

Authors:  Ian-James Malm; Clara M Olcott; Jason Y K Chan; Myriam Loyo; Young J Kim
Journal:  Am J Otolaryngol       Date:  2013-05-01       Impact factor: 1.808

4.  Undescended parathyroid adenomas as cause of persistent hyperparathyroidism.

Authors:  Paula Rioja; Germán Mateu; Leyre Lorente-Poch; Juan J Sancho; Antonio Sitges-Serra
Journal:  Gland Surg       Date:  2015-08

5.  Parathymic parathyroid: CT, US, and angiographic findings.

Authors:  J L Doppman; T H Shawker; A G Krudy; D L Miller; S J Marx; A M Spiegel; J A Norton; M F Brennan; M Schaaf; G D Aurbach
Journal:  Radiology       Date:  1985-11       Impact factor: 11.105

6.  Ectopic Undescended Parathyroid Adenoma-SPECT/CT Avoids False-Negative Interpretation on 99mTc-MIBI Dual-Phase Scintigraphy.

Authors:  Sonia Mahajan; Heiko Schoder
Journal:  Clin Nucl Med       Date:  2018-03       Impact factor: 7.794

7.  Incidence and localization of ectopic parathyroid adenomas in previously unexplored patients.

Authors:  Madhuchhanda Roy; Haggi Mazeh; Herbert Chen; Rebecca S Sippel
Journal:  World J Surg       Date:  2013-01       Impact factor: 3.352

8.  Adenomas of cervical maldescended parathyroid glands: pearls and pitfalls.

Authors:  James C Lee; Haggi Mazeh; Jonathan Serpell; Leigh W Delbridge; Herbert Chen; Stanley Sidhu
Journal:  ANZ J Surg       Date:  2012-12-10       Impact factor: 1.872

Review 9.  Ectopic parathyroid glands and their anatomical, clinical and surgical implications.

Authors:  G Noussios; P Anagnostis; K Natsis
Journal:  Exp Clin Endocrinol Diabetes       Date:  2012-11-22       Impact factor: 2.949

  9 in total

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