Literature DB >> 34084039

Misdirected ozurdex implant.

Amber Amar Bhayana1, Suneel Kumar1, Shorya Vardhan Azad1.   

Abstract

Ozurdex is one of the most commonly inserted intravitreal steroid implants in cases of posterior uveitis and recalcitrant macular edema in cases of diabetic retinopathy and vascular occlusions. Here we report accidental malpositioning of this implant in patellar fossa. Copyright:
© 2021 Oman Ophthalmic Society.

Entities:  

Keywords:  Implant; Ozurdex; misdirected

Year:  2021        PMID: 34084039      PMCID: PMC8095309          DOI: 10.4103/ojo.OJO_292_2019

Source DB:  PubMed          Journal:  Oman J Ophthalmol        ISSN: 0974-620X


A 6-year-old female, known case of juvenile idiopathic arthritis, was injected intravitreally with Ozurdex (Allergan, Irvine, CA, USA) for chronic panuveitis in the left eye which got accidentally placed anteriorly and got trapped in the anterior hyaloid face indenting the posterior capsule of the crystalline lens [Figure 1]. The eye was treated with lens sparing pars plana vitrectomy with oil insertion for developing retinal detachment and Ozurdex was explanted. Misdirected implants are rare accidental complications during intravitreal injections.[12345] Decision must be taken immediately whether to intervene to prevent vision loss due to complications.
Figure 1

Slit lamp photograph of the left eye showing anteriorly placed dexamethasone implant with inferotemporal part trapped between posterior capsule and anterior hyaloid

Slit lamp photograph of the left eye showing anteriorly placed dexamethasone implant with inferotemporal part trapped between posterior capsule and anterior hyaloid

Declaration of patient consent

The authors certify that they have obtained all appropriate patient consent forms. In the form the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.
  5 in total

1.  Vitreoretinal surgery for inadvertent intralenticular Ozurdex implant.

Authors:  K Chalioulias; M M K Muqit
Journal:  Eye (Lond)       Date:  2014-08-08       Impact factor: 3.775

2.  Accidental insertion of dexamethasone implant into the crystalline lens--12 months follow-up.

Authors:  R Chhabra; K Kopsidas; S Mahmood
Journal:  Eye (Lond)       Date:  2014-02-21       Impact factor: 3.775

3.  Accidental intralenticular dexamethasone intravitreal implant with the resolution of macular oedema in central retinal vein occlusion.

Authors:  Solmaz Abdolrahimzadeh; Pasquale Plateroti; Fabio Scarinci; Andrea Maria Plateroti
Journal:  Acta Ophthalmol       Date:  2016-04-29       Impact factor: 3.761

4.  Ozurdex completely located inside a crystallized lens - Results of 14 months.

Authors:  Burhan Baskan; Ayşe Cıcek; Ahmet Gulhan; Medine Gundogan; Sertan Goktas
Journal:  Am J Ophthalmol Case Rep       Date:  2016-08-11

5.  Pars plana vitrectomy and re-directing a dexamethasone implant into vitreous cavity following misdirected entry into the crystalline lens.

Authors:  Partha Biswas; Krishnendu Nandi; Sneha Batra; Aniket Ginodia; Preeyam Biswas
Journal:  Indian J Ophthalmol       Date:  2018-07       Impact factor: 1.848

  5 in total

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