Literature DB >> 34083309

Inter-institutional Variation in Intensity-modulated Radiotherapy for Breast Cancer in Korea (KROG 19-01).

Kyubo Kim1, Minsoo Chun2, Hyeongmin Jin2, Wonguen Jung1, Kyung Hwan Shin3, Seong Soo Shin4, Yeon Joo Kim5, Shin-Hyung Park6, Jin Hee Kim7, Yong Ho Kim8, Hyun Soo Shin9, Haeyoung Kim10, Su Ssan Kim11, Jong Hoon Lee12, Yong Bae Kim13, Sun Young Lee14, Jinhyun Choi15, DO Hoon Oh16, Ki Mun Kang17, Jeanny Kwon18, Mi Young Kim19, Taeryool Koo20, Hae Jin Park21, Sung Ja Ahn22.   

Abstract

BACKGROUND/AIM: To present the variations in the target delineation and the planning results of intensity-modulated radiation therapy (IMRT) for breast cancers. PATIENTS AND METHODS: We requested the target volumes and organs at risk delineation for two cases of left breast cancers, and evaluated the IMRT plans including the supraclavicular and internal mammary node irradiation.
RESULTS: Twenty-one institutions participated in this study. Differences in the planning target volume among institutions reached up to three-times for breast-conserving surgery (BCS) case and five-times for mastectomy case. Mean heart doses ranged from 3.3 to 24.1 Gy for BCS case and from 5.0 to 26.5 Gy for mastectomy case. Ipsilateral lung volumes receiving more than 20 Gy ranged from 4.7 to 57.4% for BCS case and from 16.4 to 55.5% for mastectomy case.
CONCLUSION: There were large variations in the target delineation and planning results of IMRT for breast cancers among institutions. Considering the increased use of breast IMRT, more standardized protocols are needed.
Copyright © 2021 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Entities:  

Keywords:  Breast cancer; dose-volume constraint; intensity-modulated radiation therapy; target volume; variation

Year:  2021        PMID: 34083309     DOI: 10.21873/anticanres.15100

Source DB:  PubMed          Journal:  Anticancer Res        ISSN: 0250-7005            Impact factor:   2.480


  1 in total

1.  Real-world analysis of manual editing of deep learning contouring in the thorax region.

Authors:  Femke Vaassen; Djamal Boukerroui; Padraig Looney; Richard Canters; Karolien Verhoeven; Stephanie Peeters; Indra Lubken; Jolein Mannens; Mark J Gooding; Wouter van Elmpt
Journal:  Phys Imaging Radiat Oncol       Date:  2022-05-14
  1 in total

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