Literature DB >> 34083191

Efficacy and safety of low-dose corticosteroid with azathioprine in the treatment of elderly-onset IgA vasculitis with nephritis.

Hikaru Sugimoto1, Yasuko Yamaguchi2, Wako Yumura2, Takashi Takei2.   

Abstract

The diagnosis of elderly-onset IgA vasculitis (IgAV) and its prognosis can be difficult to ascertain because of its rarity and the frequent presence of comorbidities. Furthermore, the treatment of elderly-onset IgAV remains controversial. We report a case of IgAV in an 87-year-old patient. Renal involvement was detected early during the IgAV follow-up. He was treated with low-dose corticosteroid and azathioprine, which led to a complete remission without any adverse effects. This suggests that precise intervention with early diagnosis and careful renal follow-up may prevent renal failure and that low-dose steroids with azathioprine can be an effective treatment for elderly-onset IgAV with nephritis. © BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ.

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Keywords:  geriatric medicine; nephrotic syndrome; vasculitis

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Year:  2021        PMID: 34083191     DOI: 10.1136/bcr-2020-241422

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  1 in total

1.  Refractory Immunoglobulin A (IgA) Vasculitis in an Elderly Patient: A Case Report.

Authors:  Nozomi Nishikura; Ryuichi Ohta; Noritaka Katagiri; Tatsuhiko Okayasu; Chiaki Sano
Journal:  Cureus       Date:  2022-09-10
  1 in total

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