Zhubin Lun1,2,3, Liwei Liu1, Guanzhong Chen1, Ming Ying1, Jin Liu1, Bo Wang1, Jingjing Liang4, Yongquan Yang1, Shiqun Chen1, Yibo He1, Edmund Y M Chung5,6, Jiyan Chen1, Jianfeng Ye7, Yong Liu8. 1. Department of Cardiology, Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, China. 2. Department of Cardiology, Dongguan TCM Hospital, Dongguan, 523000, Guangdong, China. 3. The First School of Clinical Medicine, Guangdong Medical University, Zhanjiang, 523808, China. 4. Department of Cardiology, Shunde Hospital of Southern Medical University, Shunde, China. 5. Prince of Wales Hospital, Sydney, Australia. 6. Northern Sydney Clinical School, The University of Sydney, Sydney, Australia. 7. Department of Cardiology, Dongguan TCM Hospital, Dongguan, 523000, Guangdong, China. yipjf@hotmail.com. 8. Department of Cardiology, Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, China. liuyong@gdph.org.cn.
Abstract
BACKGROUND: Contrast-associated acute kidney injury (CA-AKI) is a common complication after coronary angiography (CAG), which brings a poor prognosis. But up to now, there were fewer studies to discuss the incidence of CA-AKI comprehensively. We comprehensively explore the incidence of CA-AKI after coronary angiography. METHODS: We searched Medline, Embase, and Cochrane Database of Systematic Reviews (to 30th June 2019). We evaluated the world's incidence of the CA-AKI, and associated mortality, and to described geographic variations according to countries, regions, and economies. CA-AKI was defined as an increase in serum creatinine ≥ 0.5 mg/dl or ≥ 25% within 72 h. Random effects model meta-analyses and meta-regressions was performed to derive the sources of heterogeneity. RESULTS: A total of 134 articles (1,211,106 participants) were included in our meta-analysis. Most studies originated from China, Japan, Turkey and United States, from upper middle income and high income countries. The pooled incidence of CA-AKI after coronary angiography was 12.8% (95% CI 11.7-13.9%), and the CA-AKI associated mortality was 20.2% (95% CI 10.7-29.7%). The incidence of CA-AKI and the CA-AKI associated mortality were not declined over time (Incidence rate change: 0.23% 95% CI - 0.050 to 0.510 p = 0.617; Mortality rate change: - 1.05% 95% CI - 3.070 to 0.970 p = 0.308, respectively). CONCLUSION: CA-AKI was a universal complication in many regions, and the burden of CA-AKI remains severe. In clinical practice, physicians should pay more attention to the occurrence and active prevention and treatment of CA-AKI.
BACKGROUND: Contrast-associated acute kidney injury (CA-AKI) is a common complication after coronary angiography (CAG), which brings a poor prognosis. But up to now, there were fewer studies to discuss the incidence of CA-AKI comprehensively. We comprehensively explore the incidence of CA-AKI after coronary angiography. METHODS: We searched Medline, Embase, and Cochrane Database of Systematic Reviews (to 30th June 2019). We evaluated the world's incidence of the CA-AKI, and associated mortality, and to described geographic variations according to countries, regions, and economies. CA-AKI was defined as an increase in serum creatinine ≥ 0.5 mg/dl or ≥ 25% within 72 h. Random effects model meta-analyses and meta-regressions was performed to derive the sources of heterogeneity. RESULTS: A total of 134 articles (1,211,106 participants) were included in our meta-analysis. Most studies originated from China, Japan, Turkey and United States, from upper middle income and high income countries. The pooled incidence of CA-AKI after coronary angiography was 12.8% (95% CI 11.7-13.9%), and the CA-AKI associated mortality was 20.2% (95% CI 10.7-29.7%). The incidence of CA-AKI and the CA-AKI associated mortality were not declined over time (Incidence rate change: 0.23% 95% CI - 0.050 to 0.510 p = 0.617; Mortality rate change: - 1.05% 95% CI - 3.070 to 0.970 p = 0.308, respectively). CONCLUSION: CA-AKI was a universal complication in many regions, and the burden of CA-AKI remains severe. In clinical practice, physicians should pay more attention to the occurrence and active prevention and treatment of CA-AKI.
Authors: Noel V Guitterez; Alberto Diaz; Gerald C Timmis; William W O'Neill; Melissa A Stevens; Keisha R Sandberg; Peter A McCullough Journal: J Interv Cardiol Date: 2002-10 Impact factor: 2.279
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Authors: M R Rudnick; S Goldfarb; L Wexler; P A Ludbrook; M J Murphy; E F Halpern; J A Hill; M Winniford; M B Cohen; D B VanFossen Journal: Kidney Int Date: 1995-01 Impact factor: 10.612
Authors: Giuseppe Tarantini; Anand Prasad; Sudhir Rathore; Shweta Bansal; Regine Gottfried; Alexander R Rosenkranz; Carlo Briguori; Mohsen Yaghoubi; Atefeh Mashayekhi; Mehdi Javanbakht; Eoin Moloney Journal: Front Med (Lausanne) Date: 2022-04-25