Literature DB >> 3407546

Antioxidant effects of exogenous polyamines in damage of lysosomes inflicted by xanthine oxidase or stimulated polymorphonuclear leucocytes.

A M Kafy1, D A Lewis.   

Abstract

Active oxygen species produced by the action of xanthine oxidase or stimulated guinea-pig polymorphonuclear leucocytes have a lytic action of lysosomes possibly due to lipid peroxidation. Polyamines give some protection against lysis with putrescine being the most effective polyamine. The possible relevance to inflammatory disease is discussed.

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Year:  1988        PMID： 3407546     DOI： 10.1007/bf01968093

Source DB:  PubMed          Journal:  Agents Actions        ISSN： 0065-4299


  22 in total

1.  The role of superoxide anion generation in phagocytic bactericidal activity. Studies with normal and chronic granulomatous disease leukocytes.

Authors:  R B Johnston; B B Keele; H P Misra; J E Lehmeyer; L S Webb; R L Baehner; K V RaJagopalan
Journal:  J Clin Invest       Date:  1975-06       Impact factor: 14.808

2.  Inhibition by polyamines of lipid peroxide formation in rat liver microsomes.

Authors:  M Kitada; K Igarashi; S Hirose; H Kitagawa
Journal:  Biochem Biophys Res Commun       Date:  1979-03-30       Impact factor: 3.575

3.  In vitro interactions between endogenous polyamines and superoxide anion.

Authors:  A M Kafy; C G Haigh; D A Lewis
Journal:  Agents Actions       Date:  1986-08

4.  The stabilization-lysis action of anti-inflammatory steroids on lysosomes.

Authors:  D A Lewis; A M Symons; R J Ancill
Journal:  J Pharm Pharmacol       Date:  1970-12       Impact factor: 3.765

Review 5.  Lysosomes and joint disease.

Authors:  G Weissmann
Journal:  Arthritis Rheum       Date:  1966-12

6.  Free radicals and inflammation: superoxide-dependent activation of a neutrophil chemotactic factor in plasma.

Authors:  W F Petrone; D K English; K Wong; J M McCord
Journal:  Proc Natl Acad Sci U S A       Date:  1980-02       Impact factor: 11.205

7.  Stabilization of erythrocyte membranes by polyamines.

Authors:  S K Ballas; N Mohandas; L J Marton; S B Shohet
Journal:  Proc Natl Acad Sci U S A       Date:  1983-04       Impact factor: 11.205

8.  Putrescine--a potent endogenous anti-inflammatory substance in inflammatory exudates.

Authors:  J Bird; S Mohd-Hidir; D A Lewis
Journal:  Agents Actions       Date:  1983-06

9.  Liposome oxidation and erythrocyte lysis by enzymically generated superoxide and hydrogen peroxide.

Authors:  E W Kellogg; I Fridovich
Journal:  J Biol Chem       Date:  1977-10-10       Impact factor: 5.157

10.  Fluorescent lipid-peroxidation products in synovial fluid.

Authors:  J Lunec; T L Dormandy
Journal:  Clin Sci (Lond)       Date:  1979-01       Impact factor: 6.124
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  3 in total

1.  Studies on the antiperoxide and antihaemolytic action of polyamines using human erythrocytes.

Authors:  C Chetan; A Prabhu; V D'Souza; S B Rao
Journal:  Indian J Clin Biochem       Date:  2000-08

2.  Protective effect of spermine on DNA exposed to oxidative stress.

Authors:  C Muscari; C Guarnieri; C Stefanelli; A Giaccari; C M Caldarera
Journal:  Mol Cell Biochem       Date:  1995-03-23       Impact factor: 3.396

3.  Polyamines: Potential anti-inflammatory agents and their possible mechanism of action.

Authors:  Chakradhar V Lagishetty; Suresh Ramnath Naik
Journal:  Indian J Pharmacol       Date:  2008-06       Impact factor: 1.200
  3 in total

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