Literature DB >> 34074035

Identification of Salicylic Acid Mechanism against Leaf Blight Disease in Oryza sativa by SR-FTIR Microspectroscopic and Docking Studies.

Wannaporn Thepbandit1, Narendra Kumar Papathoti1, Jayasimha Rayalu Daddam2, Kanjana Thumanu3, Supatcharee Siriwong3, Toan Le Thanh4, Natthiya Buensanteai1.   

Abstract

The present study was to investigate the application and mechanism of pan class="Chemical">salicylic acid (SA) as SA-Ricemate for the control of leaf blight disease using a Synchrotron Radiation-based Fourier-Transform Infra-Red (SR-FTIR) microspectroscopy and docking studies. After treating rice plants cv. KDML 105 with SA-Ricemate, the leaves were inoculated with Xanthomonas oryzae pv. oryzae, the causal agent of leaf blight, and disease severity were assessed. The leaves were also used to detect changes in endogenous SA content. The results indicated that SA-Ricemate, as an activated compound, reduced disease severity by 60% at three weeks post-inoculation and increased endogenous content by 50%. The SR-FTIR analysis of changes in the mesophyll of leaves (treated and untreated) showed that the groups of lipids, pectins, and proteins amide I and amide II occurred at higher values, and polysaccharides were shown at lower values in treated compared to untreated. Besides, docking studies were used to model a three-dimensional structure for Pathogenesis-related (PR1b) protein and further identify its interaction with SA. The results showed that ASP28, ARG31, LEU32, GLN97, and ALA93 are important residues that have strong hydrogen bonds with SA. The docking results showed that SA has a good interaction, confirming its role in expression.

Entities:  

Keywords:  SR-Fourier transform infrared microspectroscopy; docking studies; induced resistance; pathogenesis-related (PR1b); rice bacterial leaf blight disease; salicylic acid

Year:  2021        PMID: 34074035     DOI: 10.3390/pathogens10060652

Source DB:  PubMed          Journal:  Pathogens        ISSN: 2076-0817


  35 in total

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  1 in total

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