Literature DB >> 34073612

The Multifaceted Nature of Nucleobindin-2 in Carcinogenesis.

Anna Skorupska1, Rafał Lenda1, Andrzej Ożyhar1, Dominika Bystranowska1.   

Abstract

Nucb2 is a multifunctional protein associated with a variety of biological processes. Multiple studies have revealed that Nucb2, and its derivative nesfatin-1, are involved in carcinogenesis. Interestingly, the role of Nucb2/nesfatin-1 in tumorigenesis seems to be dual-both pro-metastatic and anti-metastatic. The implication of Nucb2/nesfatin-1 in carcinogenesis seems to be tissue dependent. Herein, we review the role of Nucb2/nesfatin-1 in both carcinogenesis and the apoptosis process, and we also highlight the multifaceted nature of Nucb2/nesfatin-1.

Entities:  

Keywords:  Nucb2; apoptosis; biomarker; carcinogenesis; nesfatin-1; tumors

Year:  2021        PMID： 34073612     DOI： 10.3390/ijms22115687

Source DB:  PubMed          Journal:  Int J Mol Sci        ISSN： 1422-0067            Impact factor:   5.923


  85 in total

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8.  Nutrition therapy with high intensity interval training to improve prostate cancer-related fatigue in men on androgen deprivation therapy: a study protocol.

Authors:  Brenton J Baguley; Tina L Skinner; Michael D Leveritt; Olivia R L Wright
Journal:  BMC Cancer       Date:  2017-01-03       Impact factor: 4.430

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Review 10.  Targeting intrinsically disordered proteins involved in cancer.

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