Literature DB >> 34073603

Methylation and Noncoding RNAs in Gastric Cancer: Everything Is Connected.

Irina V Bure1, Marina V Nemtsova1,2.   

Abstract

Despite recent progress, gastric cancer remains one of the most common cancers and has a high mortality rate worldwide. Aberrant DNA methylation pattern and deregulation of noncoding RNA expression appear in the early stages of gastric cancer. Numerous investigations have confirmed their significant role in gastric cancer tumorigenesis and their high potential as diagnostic and prognostic biomarkers. Currently, it is clear that these epigenetic regulators do not work alone but interact with each other, generating a complex network. The aim of our review was to summarize the current knowledge of this interaction in gastric cancer and estimate its clinical potential for the diagnosis, prognosis, and treatment of the disease.

Entities:  

Keywords:  DNA methylation; biomarker; epigenetics; gastric cancer; noncoding RNAs

Year:  2021        PMID： 34073603     DOI： 10.3390/ijms22115683

Source DB:  PubMed          Journal:  Int J Mol Sci        ISSN： 1422-0067            Impact factor:   5.923


  126 in total

1.  Naturally occurring endo-siRNA silences LINE-1 retrotransposons in human cells through DNA methylation.

Authors:  Long Chen; Jane E Dahlstrom; Sung-Hun Lee; Danny Rangasamy
Journal:  Epigenetics       Date:  2012-07-01       Impact factor: 4.528

2.  MicroRNA-106a induces multidrug resistance in gastric cancer by targeting RUNX3.

Authors:  Yi Zhang; Qiping Lu; Xun Cai
Journal:  FEBS Lett       Date:  2013-08-08       Impact factor: 4.124

Review 3.  Long non-coding RNAs in gastric cancer: versatile mechanisms and potential for clinical translation.

Authors:  Jing Zhao; Yongchao Liu; Guangjian Huang; Peng Cui; Wenhong Zhang; Ying Zhang
Journal:  Am J Cancer Res       Date:  2015-02-15       Impact factor: 6.166

Review 4.  LncRNAs with miRNAs in regulation of gastric, liver, and colorectal cancers: updates in recent years.

Authors:  Chit Tam; Jack Ho Wong; Stephen Kwok Wing Tsui; Tao Zuo; Ting Fung Chan; Tzi Bun Ng
Journal:  Appl Microbiol Biotechnol       Date:  2019-05-06       Impact factor: 4.813

5.  DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes.

Authors:  Satomi Kuramochi-Miyagawa; Toshiaki Watanabe; Kengo Gotoh; Yasushi Totoki; Atsushi Toyoda; Masahito Ikawa; Noriko Asada; Kanako Kojima; Yuka Yamaguchi; Takashi W Ijiri; Kenichiro Hata; En Li; Yoichi Matsuda; Tohru Kimura; Masaru Okabe; Yoshiyuki Sakaki; Hiroyuki Sasaki; Toru Nakano
Journal:  Genes Dev       Date:  2008-04-01       Impact factor: 11.361

Review 6.  Role of miRNA-Regulated Cancer Stem Cells in the Pathogenesis of Human Malignancies.

Authors:  Abdul Q Khan; Eiman I Ahmed; Noor R Elareer; Kulsoom Junejo; Martin Steinhoff; Shahab Uddin
Journal:  Cells       Date:  2019-08-05       Impact factor: 6.600

7.  miRBase: from microRNA sequences to function.

Authors:  Ana Kozomara; Maria Birgaoanu; Sam Griffiths-Jones
Journal:  Nucleic Acids Res       Date:  2019-01-08       Impact factor: 16.971

Review 8.  The emerging role of the piRNA/piwi complex in cancer.

Authors:  Yongmei Liu; Mei Dou; Xuxia Song; Yanhan Dong; Si Liu; Haoran Liu; Jiaping Tao; Wenjing Li; Xunhua Yin; Wenhua Xu
Journal:  Mol Cancer       Date:  2019-08-09       Impact factor: 27.401

Review 9.  Epigenetic regulation of long non-coding RNAs in gastric cancer.

Authors:  Zhixia Zhou; Zhijuan Lin; Xin Pang; Muhammad Akram Tariq; Xiang Ao; Peifeng Li; Jianxun Wang
Journal:  Oncotarget       Date:  2017-12-16

Review 10.  DNA methylation in human diseases.

Authors:  Zelin Jin; Yun Liu
Journal:  Genes Dis       Date:  2018-01-31
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  6 in total

1.  A microarray expression profile and bioinformatic analysis of circular RNA in human esophageal carcinoma.

Authors:  Sina Cai; Yuqin Zhang; Xiaona Zhang; Liping Wang; Ziqing Wu; Weiyi Fang; Xiaohua Chen
Journal:  J Gastrointest Oncol       Date:  2022-04

Review 2.  Signaling pathways and therapeutic interventions in gastric cancer.

Authors:  Zi-Ning Lei; Qiu-Xu Teng; Qin Tian; Wei Chen; Yuhao Xie; Kaiming Wu; Qianlin Zeng; Leli Zeng; Yihang Pan; Zhe-Sheng Chen; Yulong He
Journal:  Signal Transduct Target Ther       Date:  2022-10-08

Review 3.  Histone Modifications and Non-Coding RNAs: Mutual Epigenetic Regulation and Role in Pathogenesis.

Authors:  Irina V Bure; Marina V Nemtsova; Ekaterina B Kuznetsova
Journal:  Int J Mol Sci       Date:  2022-05-22       Impact factor: 6.208

4.  Association between eight hypermethylation-related genes and gastric cancer: a systematic review and meta-analysis.

Authors:  Chenhui Ma; Bofang Wang; Weigao Pu; Huanhuan Ma; Kewei Song; Na Wang; Xiaobo Deng; Hao Chen
Journal:  Transl Cancer Res       Date:  2022-07       Impact factor: 0.496

Review 5.  Labeling and sequencing nucleic acid modifications using bio-orthogonal tools.

Authors:  Hui Liu; Yafen Wang; Xiang Zhou
Journal:  RSC Chem Biol       Date:  2022-06-22

Review 6.  The Role of LSD1 and LSD2 in Cancers of the Gastrointestinal System: An Update.

Authors:  Gianluca Malagraba; Mahdieh Yarmohammadi; Aadil Javed; Carles Barceló; Teresa Rubio-Tomás
Journal:  Biomolecules       Date:  2022-03-17
  6 in total

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