Literature DB >> 34072380

Subcutaneous Bupivacaine Infiltration Is Not Effective to Support Control of Postoperative Pain in Paediatric Patients Undergoing Spinal Surgery.

Anna Danielewicz1, Marek Fatyga2, Grzegorz Starobrat2, Monika Różańska-Boczula3, Magdalena Wójciak4, Ireneusz Sowa4, Sławomir Dresler4, Michał Latalski1.   

Abstract

Spinal deformity corrections in paediatric patients are long-lasting procedures involving damage to many tissues and long pain exposure; therefore, effective pain management after surgical treatment is an important issue. In this study, the effect of inclusion of local infiltration analgesia, as an integral part of the scheme in postoperative pain control, in children and adolescents, subjected to the spinal deformity correction procedure, was assessed. Thirty patients, aged 8 to 17 years, undergoing spinal deformity correction were divided into a study group, receiving a 0.25% bupivacaine solution before wound closure, and a control group (no local analgesic agent). Morphine, at the doses of 0.10 mg/kg of body weight, was administered to the patients when pain occurred. Pain scores, morphine administration, and bleeding were observed during 48 postoperative hours. The pain scores were slightly lower in a 0-4 h period in patients who received bupivacaine compared with those in the control group. However, no differences were observed in a longer period of time and in the total opioid consumption. Moreover, increasing bleeding was observed in the bupivacaine-treated patients (study group) vs. the control. Bupivacaine only modestly affects analgesia and, due to the increased bleeding observed, it should not to be part of pain control management in young patients after spinal deformity correction.

Entities:  

Keywords:  bupivacaine; pain management; scoliosis; spinal deformity

Year:  2021        PMID: 34072380     DOI: 10.3390/jcm10112407

Source DB:  PubMed          Journal:  J Clin Med        ISSN: 2077-0383            Impact factor:   4.241


  22 in total

1.  Does continuous wound infiltration enhance baseline intravenous multimodal analgesia after posterior spinal fusion surgery? A randomized, double-blinded, placebo-controlled study.

Authors:  Jules Greze; Arnaud Vighetti; Pascal Incagnoli; Jean-Louis Quesada; Pierre Albaladejo; Olivier Palombi; Jerome Tonetti; Jean-Luc Bosson; Jean-Francois Payen
Journal:  Eur Spine J       Date:  2016-02-10       Impact factor: 3.134

2.  Clinically relevant doses of lidocaine and bupivacaine do not impair cutaneous wound healing in mice.

Authors:  A Waite; S C Gilliver; G R Masterson; M J Hardman; G S Ashcroft
Journal:  Br J Anaesth       Date:  2010-04-24       Impact factor: 9.166

3.  Port Site Local Anesthetic Infiltration Vs Single-dose Intrathecal Opioid Injection to Control Perioperative Pain in Children Undergoing Minimal Invasive Surgery: A Comparative Analysis.

Authors:  Arun K Srinivasan; Dhiren Shrivastava; Rebecca E Kurzweil; Dana A Weiss; Christopher J Long; Aseem R Shukla
Journal:  Urology       Date:  2016-07-20       Impact factor: 2.649

4.  Liposomal bupivacaine incisional injection in single-level lumbar spine surgery.

Authors:  Ross C Puffer; Kevin Tou; Rose E Winkel; Mohamad Bydon; Bradford Currier; Brett A Freedman
Journal:  Spine J       Date:  2016-06-24       Impact factor: 4.166

5.  The effect of a peripheral block on inflammation-induced prostaglandin E2 and cyclooxygenase expression in rats.

Authors:  Hélène Beloeil; Marc Gentili; Dan Benhamou; Jean-Xavier Mazoit
Journal:  Anesth Analg       Date:  2009-09       Impact factor: 5.108

6.  Effect of topical local anesthetic application to skin harvest sites for pain management in burn patients undergoing skin-grafting procedures.

Authors:  W S Jellish; R L Gamelli; P A Furry; V L McGill; E M Fluder
Journal:  Ann Surg       Date:  1999-01       Impact factor: 12.969

7.  Single periarticular local infiltration analgesia reduces opiate consumption until 48 hours after total knee arthroplasty. A randomized placebo-controlled trial involving 56 patients.

Authors:  Mika Niemeläinen; Jarkko Kalliovalkama; Antti J Aho; Teemu Moilanen; Antti Eskelinen
Journal:  Acta Orthop       Date:  2014-09-19       Impact factor: 3.717

8.  Evaluation of Anesthesia Profile in Pediatric Patients after Inguinal Hernia Repair with Caudal Block or Local Wound Infiltration.

Authors:  Aleksandra Gavrilovska-Brzanov; Biljana Kuzmanovska; Andrijan Kartalov; Ljupco Donev; Albert Lleshi; Marija Jovanovski-Srceva; Tatjana Spirovska; Nikola Brzanov; Risto Simeonov
Journal:  Open Access Maced J Med Sci       Date:  2016-02-03

9.  Adolescent Idiopathic Scoliosis.

Authors:  Muhammad Naghman Choudhry; Zafar Ahmad; Rajat Verma
Journal:  Open Orthop J       Date:  2016-05-30

Review 10.  Basics and Best Practices of Multimodal Pain Management for the Plastic Surgeon.

Authors:  Jenny C Barker; Girish P Joshi; Jeffrey E Janis
Journal:  Plast Reconstr Surg Glob Open       Date:  2020-05-26
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