Literature DB >> 34071871

Frailty Assessment in a Cohort of Elderly Patients with Severe Symptomatic Aortic Stenosis: Insights from the FRailty Evaluation in Severe Aortic Stenosis (FRESAS) Registry.

Pablo Solla-Suárez1,2, Pablo Avanzas2,3,4, Isaac Pascual2,3,5, Manuel Bermúdez-Menéndez De La Granda1,2, Marcel Almendarez2,3, Jose M Arche-Coto1,2, Daniel Hernández-Vaquero2,3, Rebeca Lorca2,3, Eva López-Álvarez1,2, Rut Álvarez-Velasco2,3, Carmen Moreno-Planillo1, César Morís de la Tassa2,3,4, José Gutiérrez-Rodríguez2,3.   

Abstract

BACKGROUND: Precise evaluation of the degree of frailty is a fundamental part of the global geriatric assessment that helps to avoid therapies that could be futile. Our main objective was to determine the prevalence of frailty in a specific consult of patients undergoing aortic valve replacement.
METHODS: From May 2018 to February 2020, all consecutive patients ≥75 years old, with severe symptomatic aortic stenosis, undergoing valve replacement in the Principality of Asturias (Northern Spain) were evaluated.
RESULTS: A total of 286 patients were assessed. The mean age was 84 ± 4.01 years old; 175 (61.2%) were female. The short performance physical battery score was 8.5 ± 2.4 and the prevalence of frailty was 19.6% (56 patients). In the multivariable analysis, age, Barthel index and atrial fibrillation were independent predictors of frailty.
CONCLUSIONS: The prevalence of frailty in our sample patients undergoing aortic valve replacement, evaluated by a standardized protocol, was 19.6%.

Entities:  

Keywords:  Transcatheter Aortic Valve Implantation (TAVR); aortic stenosis; frailty; transcatheter aortic valve replacement (TAVI)

Year:  2021        PMID: 34071871     DOI: 10.3390/jcm10112345

Source DB:  PubMed          Journal:  J Clin Med        ISSN: 2077-0383            Impact factor:   4.241


  26 in total

Review 1.  [Non-cardiac aspects of aortic stenosis in the elderly: A review].

Authors:  Baldomero Álvarez-Fernández; Francesç Formiga; Manuel de Mora-Martín; Fernando Calleja; Ricardo Gómez-Huelgas
Journal:  Rev Esp Geriatr Gerontol       Date:  2016-07-16

2.  The Erasmus Frailty Score is associated with delirium and 1-year mortality after Transcatheter Aortic Valve Implantation in older patients. The TAVI Care & Cure program.

Authors:  Jeannette A Goudzwaard; Marjo J A G de Ronde-Tillmans; Nahid El Faquir; Ferhat Acar; Nicolas M Van Mieghem; Mattie J Lenzen; Peter P T de Jaegere; Francesco U S Mattace-Raso
Journal:  Int J Cardiol       Date:  2018-10-28       Impact factor: 4.164

3.  Habitual Physical Activity in Older Adults Undergoing TAVR: Insights From the FRAILTY-AVR Study.

Authors:  Janarthanan Sathananthan; Sandra Lauck; Nicolo Piazza; Giuseppe Martucci; Dae H Kim; Jeffrey J Popma; Anita W Asgar; Louis P Perrault; Thierry Lefèvre; Marino Labinaz; Andre Lamy; Mark D Peterson; Rakesh C Arora; Nicolas Noiseux; Philippe Généreux; John G Webb; Jonathan Afilalo
Journal:  JACC Cardiovasc Interv       Date:  2019-04-22       Impact factor: 11.195

4.  Using a multidimensional prognostic index (MPI) based on comprehensive geriatric assessment (CGA) to predict mortality in elderly undergoing transcatheter aortic valve implantation.

Authors:  Marie-Laure Bureau; Evelyne Liuu; Luc Christiaens; Alberto Pilotto; Jean Mergy; Fabienne Bellarbre; Pierre Ingrand; Marc Paccalin
Journal:  Int J Cardiol       Date:  2017-02-16       Impact factor: 4.164

5.  2017 ESC/EACTS Guidelines for the management of valvular heart disease.

Authors:  Helmut Baumgartner; Volkmar Falk; Jeroen J Bax; Michele De Bonis; Christian Hamm; Per Johan Holm; Bernard Iung; Patrizio Lancellotti; Emmanuel Lansac; Daniel Rodriguez Muñoz; Raphael Rosenhek; Johan Sjögren; Pilar Tornos Mas; Alec Vahanian; Thomas Walther; Olaf Wendler; Stephan Windecker; Jose Luis Zamorano
Journal:  Eur Heart J       Date:  2017-09-21       Impact factor: 29.983

6.  Frailty in Older Adults Undergoing Aortic Valve Replacement: The FRAILTY-AVR Study.

Authors:  Jonathan Afilalo; Sandra Lauck; Dae H Kim; Thierry Lefèvre; Nicolo Piazza; Kevin Lachapelle; Giuseppe Martucci; Andre Lamy; Marino Labinaz; Mark D Peterson; Rakesh C Arora; Nicolas Noiseux; Andrew Rassi; Igor F Palacios; Philippe Généreux; Brian R Lindman; Anita W Asgar; Caroline A Kim; Amanda Trnkus; José A Morais; Yves Langlois; Lawrence G Rudski; Jean-Francois Morin; Jeffrey J Popma; John G Webb; Louis P Perrault
Journal:  J Am Coll Cardiol       Date:  2017-07-07       Impact factor: 24.094

7.  Relation of frailty to outcomes after transcatheter aortic valve replacement (from the PARTNER trial).

Authors:  Philip Green; Suzanne V Arnold; David J Cohen; Ajay J Kirtane; Susheel K Kodali; David L Brown; Charanjit S Rihal; Ke Xu; Yang Lei; Marian C Hawkey; Rebeca J Kim; Maria C Alu; Martin B Leon; Michael J Mack
Journal:  Am J Cardiol       Date:  2015-04-18       Impact factor: 2.778

8.  Prediction of Poor Outcome After Transcatheter Aortic Valve Replacement.

Authors:  Suzanne V Arnold; Jonathan Afilalo; John A Spertus; Yuanyuan Tang; Suzanne J Baron; Philip G Jones; Michael J Reardon; Steven J Yakubov; David H Adams; David J Cohen
Journal:  J Am Coll Cardiol       Date:  2016-10-25       Impact factor: 24.094

9.  Role of inflammation and oxidative stress in atrial fibrillation.

Authors:  Jie Li; Joseph Solus; Qingxia Chen; Young Hee Rho; Ginger Milne; C Michael Stein; Dawood Darbar
Journal:  Heart Rhythm       Date:  2009-12-24       Impact factor: 6.343

10.  Measures of physical performance and risk for progressive and catastrophic disability: results from the Women's Health and Aging Study.

Authors:  Graziano Onder; Brenda W J H Penninx; Luigi Ferrucci; Linda P Fried; Jack M Guralnik; Marco Pahor
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2005-01       Impact factor: 6.053

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