Literature DB >> 34070245

A New Proximal Femur Reconstruction Technique after Bone Tumor Resection in a Very Small Patient: An Exemplificative Case.

Carmine Zoccali1, Silvia Careri2, Dario Attala3, Michela Florio2, Giuseppe Maria Milano4, Marco Giordano2.   

Abstract

For patients too young to be fitted with an expandable prosthesis, limb salvage surgery requires other strategies. The main problems are related to the impossibility of implanting an expandable prosthesis to the residual bone growth that is much too big in relation to the bone size, with the precocious implant loosening and/or the residual absence of bone growth, as well as the problem of limb length and shape difference. In this paper, we report a possible reconstruction solution using a composite prosthesis for an Ewing's sarcoma of the proximal femur in an infant patient. After resection, a femoral stem was cemented into the distal third of a homoplastic humerus; a carbon fiber plate was used to stabilize the bone/homograft interface. At the one-year follow-up, the patient was free of disease and able to walk with only a slight limp. This case report describes a possible solution for very small patients. An adult humerus is of the right size to replace a child's lower limb segments, and the distal humerus can be shaped, maintaining a cortex stiff enough to support a prosthesis. Very young patients might obtain a faster osteointegration of the graft than adults, due to their higher biological activity and, in this case, the diapasonal shape of the allograft might also have contributed to accelerated fusion. Moreover, the use of a graft to fit the prosthesis avoids loosening issues due to canal widening, hypothetically providing more growing time before system failure and revision surgery. However, although this technique is promising, further studies are necessary to confirm our findings and to verify if this procedure allows easier future prosthesis implantation.

Entities:  

Keywords:  Ewing’s sarcoma; bone tumors; children; composite prosthesis; infants

Year:  2021        PMID: 34070245     DOI: 10.3390/children8060442

Source DB:  PubMed          Journal:  Children (Basel)        ISSN: 2227-9067


  18 in total

1.  Combination of Extracorporeally-irradiated Autograft and Vascularized Bone Graft for Reconstruction of Malignant Musculoskeletal Tumor.

Authors:  Atsushi Mihara; Keiichi Muramatsu; Takahiro Hashimoto; Ryuta Iwanaga; Koichiro Ihara; Takashi Sakai
Journal:  Anticancer Res       Date:  2020-03       Impact factor: 2.480

Review 2.  Joint-preservation surgery for pediatric osteosarcoma of the knee joint.

Authors:  Akihiko Takeuchi; Norio Yamamoto; Katsuhiro Hayashi; Hidenori Matsubara; Shinji Miwa; Kentaro Igarashi; Hiroyuki Tsuchiya
Journal:  Cancer Metastasis Rev       Date:  2019-12       Impact factor: 9.264

Review 3.  Expandable endoprostheses in malignant bone tumors in children: indications and limitations.

Authors:  Rainer Baumgart; Ulrich Lenze
Journal:  Recent Results Cancer Res       Date:  2009

4.  Original biological reconstruction of the hip in a 4-year-old girl.

Authors:  Marco Manfrini; Marco Innocenti; Massimo Ceruso; Mario Mercuri
Journal:  Lancet       Date:  2003-01-11       Impact factor: 79.321

5.  Non-invasive expandable prosthesis in musculoskeletal oncology paediatric patients for the distal and proximal femur. First results.

Authors:  Ferran Torner; Josep M Segur; Rosendo Ullot; Francisco Soldado; Pedro Domenech; Lydia DeSena; Jorge Knorr
Journal:  Int Orthop       Date:  2016-03-21       Impact factor: 3.075

6.  Dose-intensified compared with standard chemotherapy for nonmetastatic Ewing sarcoma family of tumors: a Children's Oncology Group Study.

Authors:  Linda Granowetter; Richard Womer; Meenakshi Devidas; Mark Krailo; Chenguang Wang; Mark Bernstein; Neyssa Marina; Patrick Leavey; Mark Gebhardt; John Healey; Robert Cooper Shamberger; Allen Goorin; James Miser; James Meyer; Carola A S Arndt; Scott Sailer; Karen Marcus; Elizabeth Perlman; Paul Dickman; Holcombe E Grier
Journal:  J Clin Oncol       Date:  2009-04-06       Impact factor: 44.544

Review 7.  Adjuvant and neoadjuvant combination chemotherapy for osteogenic sarcoma.

Authors:  Stefano Ferrari; Emanuela Palmerini
Journal:  Curr Opin Oncol       Date:  2007-07       Impact factor: 3.645

8.  Long-term outcomes of non-invasive expandable endoprostheses for primary malignant tumors around the knee in skeletally-immature patients.

Authors:  Ruben Dukan; Eric Mascard; Tristan Langlais; Younes Ouchrif; Christophe Glorion; Stéphanie Pannier; Charlie Bouthors
Journal:  Arch Orthop Trauma Surg       Date:  2021-01-08       Impact factor: 3.067

Review 9.  Current review of surgical management options for extremity bone sarcomas.

Authors:  Catalin Cirstoiu; Bogdan Cretu; Bogdan Serban; Zsombor Panti; Mihai Nica
Journal:  EFORT Open Rev       Date:  2019-05-10

Review 10.  Current Status of Management and Outcome for Patients with Ewing Sarcoma.

Authors:  Asle Charles Hesla; Andri Papakonstantinou; Panagiotis Tsagkozis
Journal:  Cancers (Basel)       Date:  2021-03-10       Impact factor: 6.639

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  1 in total

1.  Bone Development and Disease in Infants.

Authors:  Vito Pavone
Journal:  Children (Basel)       Date:  2022-04-06
  1 in total

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