Literature DB >> 3406935

HLA-linked susceptibility to rheumatoid arthritis in north India.

N K Mehra1, R Kaul, V Taneja, T K Chaudhuri, B Jhinghan, A N Malaviya.   

Abstract

Nine multiplex RA families of North Indian origin were tissue typed to determine the segregation of parental haplotypes among sibs. The assortment of haplotypes in 18 affected sibs was not random, with seven sib pairs being HLA identical and two haploidentical with the proband (P = 0.0007). HLA-DR4 occurred in eight out of nine probands (88.8%) and in 11 out of 13 familial RA subjects (84.6%).

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Year:  1988        PMID: 3406935     DOI: 10.1111/j.1399-0039.1988.tb02084.x

Source DB:  PubMed          Journal:  Tissue Antigens        ISSN: 0001-2815


  3 in total

Review 1.  The immunogenetics of rheumatoid arthritis.

Authors:  B P Wordsworth; J I Bell
Journal:  Springer Semin Immunopathol       Date:  1992

Review 2.  Polygenic susceptibility in rheumatoid arthritis.

Authors:  P Wordsworth; J Bell
Journal:  Ann Rheum Dis       Date:  1991-06       Impact factor: 19.103

3.  HLA-DR1 and DRw6 association in DR4-negative rheumatoid arthritis patients.

Authors:  B Lang; I Melchers; A Urlacher; R F Tanzi-Fetta; S Kohlbrenner; M M Tongio; H H Peter
Journal:  Rheumatol Int       Date:  1990       Impact factor: 2.631

  3 in total

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