| Literature DB >> 34064217 |
Marten Schulz1, Lam Giang Vuong2, Hans Peter Müller3, Martin Maibier1, Frank Tacke1, Igor Wolfgang Blau2, Alexander Wree1.
Abstract
Hepatic sinusoidal obstruction syndrome (SOS), also known as veno-occlusive disease (VOD) can be a life-threatening complication after hematopoietic stem cell transplantation (HSCT). Diagnosis is often difficult and traditionally based on clinical parameters. Shear wave elastography (SWE) is a modern non-invasive liver stiffness measurement technique using ultrasound. In this monocentric study, we evaluated the role of SWE in diagnosing SOS/VOD in 63 adult patients undergoing HSCT from February 2020 to August 2020 in real world settings. Three patients developed SOS/VOD. This was accompanied by an increase in shear wave velocity in all three patients, indicating that this method may contribute to establishing the diagnosis SOS/VOD after HSCT.Entities:
Keywords: hematopoietic stem cell transplantation (HSCT); liver stiffness measurement (LSM); shear wave elastography (SWE); sinusoidal obstruction syndrome (SOS); veno-occlusive disease (VOD)
Year: 2021 PMID: 34064217 DOI: 10.3390/diagnostics11060928
Source DB: PubMed Journal: Diagnostics (Basel) ISSN: 2075-4418