Maximilian Koeppel1, Katlynn Mathis2, Kathryn H Schmitz3, Joachim Wiskemann4. 1. Institute of Sports and Sport Science, Heidelberg University, Im Neuenheimer Feld 700, 69120, Heidelberg, Germany; Working Group Exercise Oncology, Division of Medical Oncology, National Center for Tumor Diseases Heidelberg (NCT Heidelberg) and Heidelberg University Hospital, Im Neuenheimer Feld 460, 69120, Heidelberg, Germany; Penn State College of Medicine, University Drive 500, 17033, Hershey, PA, USA. 2. Penn State College of Medicine, University Drive 500, 17033, Hershey, PA, USA; Harrisburg Area Community College, Bldg. YL150, 17401, YORK, PA, USA. 3. Penn State College of Medicine, University Drive 500, 17033, Hershey, PA, USA. 4. Penn State College of Medicine, University Drive 500, 17033, Hershey, PA, USA; Harrisburg Area Community College, Bldg. YL150, 17401, YORK, PA, USA. Electronic address: Joachim.wiskemann@nct-heidelberg.de.
Abstract
BACKGROUND: Muscle wasting has a negative effect on treatment toxicity and cancer prognosis. Resistance training appears to be a promising approach to counteract the loss of muscle mass. METHODS: Pubmed, Cochrane Library, SportDiscus and CINAHL. Randomized controlled resistance training trials with cancer survivros where eligible if lean body mass (LBM) or muscle mass were assessed. RESULTS: A total of 34 trials were included into the primary analysis. Compared to the control individuals, the intervention groups show a superiority in LBM of 0.85 kg (95 % CI = 0.26-1.43, p = .004). Isolated, the participants in the intervention groups show an increase in LBM of 0.51 kg (95 % CI = -0.05-1.06, p = .072); the control groups displayed a decrease of -0.59 kg (95 % CI= -1.04 to 0.06, p = .078). Supervision displayed an mediating role. CONCLUSIONS: Resistance training can counteract the loss of muscle mass in cancer patients. Especially in a supervised setting.
BACKGROUND: Muscle wasting has a negative effect on treatment toxicity and cancer prognosis. Resistance training appears to be a promising approach to counteract the loss of muscle mass. METHODS: Pubmed, Cochrane Library, SportDiscus and CINAHL. Randomized controlled resistance training trials with cancer survivros where eligible if lean body mass (LBM) or muscle mass were assessed. RESULTS: A total of 34 trials were included into the primary analysis. Compared to the control individuals, the intervention groups show a superiority in LBM of 0.85 kg (95 % CI = 0.26-1.43, p = .004). Isolated, the participants in the intervention groups show an increase in LBM of 0.51 kg (95 % CI = -0.05-1.06, p = .072); the control groups displayed a decrease of -0.59 kg (95 % CI= -1.04 to 0.06, p = .078). Supervision displayed an mediating role. CONCLUSIONS: Resistance training can counteract the loss of muscle mass in cancer patients. Especially in a supervised setting.
Authors: Carla M Prado; Camila E Orsso; Suzette L Pereira; Philip J Atherton; Nicolaas E P Deutz Journal: J Cachexia Sarcopenia Muscle Date: 2022-03-17 Impact factor: 12.063
Authors: Kelcey A Bland; Meinir Krishnasamy; Evelyn B Parr; Stella Mulder; Peter Martin; Luc J C van Loon; Prue Cormie; Natasha Michael; Eva M Zopf Journal: BMC Palliat Care Date: 2022-05-17 Impact factor: 3.113
Authors: Changhyun Lim; Everson A Nunes; Brad S Currier; Jonathan C McLeod; Aaron C Q Thomas; Stuart M Phillips Journal: Med Sci Sports Exerc Date: 2022-04-06
Authors: Adrian Escriche-Escuder; Manuel Trinidad-Fernández; Bella Pajares; Marcos Iglesias-Campos; Emilio Alba; José Manuel García-Almeida; Cristina Roldán-Jiménez; Antonio I Cuesta-Vargas Journal: Sci Rep Date: 2022-09-07 Impact factor: 4.996