Literature DB >> 3406210

Molecular analysis of hemoglobin H disease in Taiwan.

H H Lee1, W F Cheung, J G Chang, T C Liu, W Y Leung, H T Ng, K B Choo.   

Abstract

The molecular basis of seven Chinese patients in Taiwan with hemoglobin H disease was investigated and was found to be heterogeneous in the mutation type. They were alpha-thalassemia-1 mutation combined with hemoglobin Constant Spring, an undetermined nondeletion form of alpha-thalassemia and a deletion form of alpha-thalassemia-2 mutations. The alpha-thalassemia-1 mutation was shown to be the --SEA type I haplotype.

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Year:  1988        PMID： 3406210

Source DB:  PubMed          Journal:  Proc Natl Sci Counc Repub China B        ISSN： 0255-6596


  2 in total

1.  Rapid molecular characterization of Hb H disease in Chinese by polymerase chain reaction.

Authors:  J G Chang; T C Liu; L I Perng; S S Chiou; T P Chen; P H Chen; C P Lin
Journal:  Ann Hematol       Date:  1994-01       Impact factor: 3.673

2.  Rapid detection of -alpha 4.2 deletion of alpha-thalassemia-2 by polymerase chain reaction.

Authors:  J G Chang; T C Liu; S S Chiou; J T Chen; T P Chen; C P Lin
Journal:  Ann Hematol       Date:  1994-10       Impact factor: 3.673
  2 in total

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