Literature DB >> 34060897

Genomic Characterization of Klebsiella quasipneumoniae from Clinical Specimens in Singapore.

Ka Lip Chew1, Sophie Octavia2, Deborah Lai3, Raymond T P Lin1,2, Jeanette W P Teo1.   

Abstract

A total of 1,281 specimens from 1,024 patients were screened. Phylogenetic analysis classified 44 of these isolates as Klebsiella quasipneumoniae subsp. similipneumoniae (44/1,281 [3.4%]) and the remaining three as K. quasipneumoniae subsp. quasipneumoniae. The most common specimen source was urine (21/47 [44.7%]) followed by blood (14/47 [29.8%]). K. quasipneumoniae isolates were nonclonal. Carbapenemase-encoding genes (blaNDM and blaOXA-181) were detected in only two isolates (2/47 [4.3%]). K. quasipneumoniae appears to cause a spectrum of infections similar to those of K. pneumoniae, although higher rates of susceptibility to many commonly tested antimicrobials and low prevalence of virulence genes were demonstrated.

Entities:  

Keywords:  Enterobacteriaceae; antimicrobial resistance; clinical microbiology; whole genome

Mesh：

Substances：

Year:  2021        PMID： 34060897      PMCID： PMC8284435          DOI： 10.1128/AAC.00412-21

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  29 in total

1.  Development of a rapid identification method for Klebsiella pneumoniae phylogenetic groups and analysis of 420 clinical isolates.

Authors:  S Brisse; T van Himbergen; K Kusters; J Verhoef
Journal:  Clin Microbiol Infect       Date:  2004-10       Impact factor: 8.067

2.  Description of Klebsiella quasipneumoniae sp. nov., isolated from human infections, with two subspecies, Klebsiella quasipneumoniae subsp. quasipneumoniae subsp. nov. and Klebsiella quasipneumoniae subsp. similipneumoniae subsp. nov., and demonstration that Klebsiella singaporensis is a junior heterotypic synonym of Klebsiella variicola.

Authors:  Sylvain Brisse; Virginie Passet; Patrick A D Grimont
Journal:  Int J Syst Evol Microbiol       Date:  2014-06-23       Impact factor: 2.747

3.  Genomic analysis of diversity, population structure, virulence, and antimicrobial resistance in Klebsiella pneumoniae, an urgent threat to public health.

Authors:  Kathryn E Holt; Heiman Wertheim; Ruth N Zadoks; Stephen Baker; Chris A Whitehouse; David Dance; Adam Jenney; Thomas R Connor; Li Yang Hsu; Juliëtte Severin; Sylvain Brisse; Hanwei Cao; Jonathan Wilksch; Claire Gorrie; Mark B Schultz; David J Edwards; Kinh Van Nguyen; Trung Vu Nguyen; Trinh Tuyet Dao; Martijn Mensink; Vien Le Minh; Nguyen Thi Khanh Nhu; Constance Schultsz; Kuntaman Kuntaman; Paul N Newton; Catrin E Moore; Richard A Strugnell; Nicholas R Thomson
Journal:  Proc Natl Acad Sci U S A       Date:  2015-06-22       Impact factor: 11.205

4.  Klebsiella variicola, a novel species with clinical and plant-associated isolates.

Authors:  Mónica Rosenblueth; Lucía Martínez; Jesús Silva; Esperanza Martínez-Romero
Journal:  Syst Appl Microbiol       Date:  2004-02       Impact factor: 4.022

5.  Interactive tree of life (iTOL) v3: an online tool for the display and annotation of phylogenetic and other trees.

Authors:  Ivica Letunic; Peer Bork
Journal:  Nucleic Acids Res       Date:  2016-04-19       Impact factor: 16.971

6.  Differential host susceptibility and bacterial virulence factors driving Klebsiella liver abscess in an ethnically diverse population.

Authors:  I Russel Lee; James S Molton; Kelly L Wyres; Claire Gorrie; Jocelyn Wong; Chu Han Hoh; Jeanette Teo; Shirin Kalimuddin; David C Lye; Sophia Archuleta; Kathryn E Holt; Yunn-Hwen Gan
Journal:  Sci Rep       Date:  2016-07-13       Impact factor: 4.379

Review 7.  Klebsiella pneumoniae in Singapore: Hypervirulent Infections and the Carbapenemase Threat.

Authors:  Ka Lip Chew; Raymond T P Lin; Jeanette W P Teo
Journal:  Front Cell Infect Microbiol       Date:  2017-12-12       Impact factor: 5.293

8.  Genetic diversity, mobilisation and spread of the yersiniabactin-encoding mobile element ICEKp in Klebsiella pneumoniae populations.

Authors:  Margaret M C Lam; Ryan R Wick; Kelly L Wyres; Claire L Gorrie; Louise M Judd; Adam W J Jenney; Sylvain Brisse; Kathryn E Holt
Journal:  Microb Genom       Date:  2018-07-09

9.  Klebsiella quasipneumoniae Provides a Window into Carbapenemase Gene Transfer, Plasmid Rearrangements, and Patient Interactions with the Hospital Environment.

Authors:  Amy J Mathers; Derrick Crook; Alison Vaughan; Katie E Barry; Kasi Vegesana; Nicole Stoesser; Hardik I Parikh; Robert Sebra; Shireen Kotay; A Sarah Walker; Anna E Sheppard
Journal:  Antimicrob Agents Chemother       Date:  2019-05-24       Impact factor: 5.191

10.  Forensic genomics of a novel Klebsiella quasipneumoniae type from a neonatal intensive care unit in China reveals patterns of colonization, evolution and epidemiology.

Authors:  Laura Perlaza-Jiménez; Qing Wu; Von Vergel L Torres; Xiaoxiao Zhang; Jiahui Li; Andrea Rocker; Trevor Lithgow; Tieli Zhou; Dhanasekaran Vijaykrishna
Journal:  Microb Genom       Date:  2020-10
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  2 in total

1.  Complete Genome Sequence of Klebsiella quasipneumoniae MMCC7, Isolated from an Eclectus Parrot (Eclectus roratus).

Authors:  M M C Cheng; G K K Lai; S D J Griffin; F C C Leung
Journal:  Microbiol Resour Announc       Date:  2022-04-25

2.  Role of Klebsiella pneumoniae Type VI secretion system (T6SS) in long-term gastrointestinal colonization.

Authors:  Thomas Merciecca; Stéphanie Bornes; Laurence Nakusi; Sébastien Theil; Olaya Rendueles; Christiane Forestier; Sylvie Miquel
Journal:  Sci Rep       Date:  2022-10-10       Impact factor: 4.996
  2 in total

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