Literature DB >> 340585

Cell surface immunoglobulin XXI. appearance of IgD on murine lymphocytes during differentiation.

D Yuan, E S Vitetta.   

Abstract

The differentiation of Ig-bearing lymphocytes in adult mice was studied by monitoring the appearance of IgD relative to IgM on the surface of splenocytes obtained from lethally irradiated animals reconstituted for various periods of time with adult bone marrow cells, neonatal splenocytes, or Ig- adult splenocytes. It was found that IgM appears before IgD on differentiating lymphocytes. Furthermore, the rate of appearance of IgD during differentiation of adult cells is similar to that observed with neonatal cells.

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Year:  1978        PMID： 340585

Source DB:  PubMed          Journal:  J Immunol        ISSN： 0022-1767            Impact factor:   5.422


  5 in total

1.  Kinetics of sequential appearance of IgM and IgD on B lymphocytes in the bone marrow of the adult mouse.

Authors:  R Aspinall; J J Owen
Journal:  Immunology       Date:  1983-02       Impact factor: 7.397

2.  Regulation of immunoglobulin D synthesis in murine neonatal B lymphocytes.

Authors:  D Yuan
Journal:  Mol Cell Biol       Date:  1986-04       Impact factor: 4.272

3.  Molecular components of the B cell antigen receptor complex of class IgD differ partly from those of IgM.

Authors:  J Wienands; J Hombach; A Radbruch; C Riesterer; M Reth
Journal:  EMBO J       Date:  1990-02       Impact factor: 11.598

Review 4.  Immune system as a target organ for toxicity.

Authors:  P H Bick
Journal:  Environ Health Perspect       Date:  1982-02       Impact factor: 9.031

5.  Immunoglobulin M and D antigen receptors are both capable of mediating B lymphocyte activation, deletion, or anergy after interaction with specific antigen.

Authors:  R Brink; C C Goodnow; J Crosbie; E Adams; J Eris; D Y Mason; S B Hartley; A Basten
Journal:  J Exp Med       Date:  1992-10-01       Impact factor: 14.307
  5 in total

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