Literature DB >> 34055333

Hopes and fears before opioid tapering: a quantitative and qualitative study of patients with chronic pain and long-term opioids.

Jane Quinlan1,2, Heather Willson2, Katheryn Grange1.   

Abstract

BACKGROUND: It is clear that the risks of opioids in chronic pain outweigh the benefits, creating a drive for clinicians to support patients taper and stop long-term opioids. However, it is not known how patients who have been taking these medicines for months or years feel about reducing them. Using quantitative and qualitative data, this study describes the psychological complexity of these patients and examines their hopes and fears before opioid reduction.
METHODS: Sixty patients attending the opioid clinic completed psychological and pain questionnaires, providing quantitative data, just before they commenced opioid tapering. They scored the severity of opioid side effects and completed a free text framework to express their beliefs about stopping or continuing opioids. A phenomenological approach was used to identify common qualitative themes.
RESULTS: Most patients were taking opioid doses above the UK recommended maximum dose and reported severe pain with high pain interference. Over 80% of patients described significant depression and 60% significant anxiety. Negative themes around stopping opioids were more common than positive ones, with 63% patients fearing increased pain. A quarter of patients referred to addiction and 16% feared withdrawal. Five patients hoped for a better quality of life; seven feared a worse one. Opioid side effects were common and severe.
CONCLUSION: Patients with chronic pain taking long-term opioids demonstrate high psychological distress and low self-efficacy. Their concerns around opioid tapering relate to pain, quality of life and withdrawal. Identifying and addressing patients' individual concerns should increase the likelihood of successful opioid tapering. © The British Pain Society 2020.

Entities:  

Keywords:  Qualitative research; anxiety; chronic pain; depression; opioid dependence; opioid taper; opioids; pain catastrophizing; psychological distress; self-efficacy

Year:  2020        PMID: 34055333      PMCID: PMC8138618          DOI: 10.1177/2049463720974053

Source DB:  PubMed          Journal:  Br J Pain        ISSN: 2049-4637


  29 in total

Review 1.  Theoretical perspectives on the relation between catastrophizing and pain.

Authors:  M J Sullivan; B Thorn; J A Haythornthwaite; F Keefe; M Martin; L A Bradley; J C Lefebvre
Journal:  Clin J Pain       Date:  2001-03       Impact factor: 3.442

2.  Normative data for common pain measures in chronic pain clinic populations: closing a gap for clinicians and researchers.

Authors:  Michael K Nicholas; Daniel S J Costa; Megan Blanchard; Hilarie Tardif; Ali Asghari; Fiona M Blyth
Journal:  Pain       Date:  2019-05       Impact factor: 6.961

3.  Impact of opioid dose escalation on pain intensity: a retrospective cohort study.

Authors:  Corey J Hayes; Erin E Krebs; Teresa Hudson; Joshua Brown; Chenghui Li; Bradley C Martin
Journal:  Pain       Date:  2020-05       Impact factor: 6.961

4.  Alterations in brain structure and functional connectivity in prescription opioid-dependent patients.

Authors:  Jaymin Upadhyay; Nasim Maleki; Jennifer Potter; Igor Elman; David Rudrauf; Jaime Knudsen; Diana Wallin; Gautam Pendse; Leah McDonald; Margaret Griffin; Julie Anderson; Lauren Nutile; Perry Renshaw; Roger Weiss; Lino Becerra; David Borsook
Journal:  Brain       Date:  2010-06-16       Impact factor: 13.501

5.  A brief measure for assessing generalized anxiety disorder: the GAD-7.

Authors:  Robert L Spitzer; Kurt Kroenke; Janet B W Williams; Bernd Löwe
Journal:  Arch Intern Med       Date:  2006-05-22

6.  Psychiatric Disorders Among Patients Seeking Treatment for Co-Occurring Chronic Pain and Opioid Use Disorder.

Authors:  Declan T Barry; Christopher J Cutter; Mark Beitel; Robert D Kerns; Christopher Liong; Richard S Schottenfeld
Journal:  J Clin Psychiatry       Date:  2016-10       Impact factor: 4.384

7.  Depressive symptoms and pain evaluations among persons with chronic pain: catastrophizing, but not pain acceptance, shows significant effects.

Authors:  Elizabeth J Richardson; Timothy J Ness; Daniel M Doleys; James H Baños; Leanne Cianfrini; J Scott Richards
Journal:  Pain       Date:  2009-09-20       Impact factor: 6.961

8.  Quality of life associated with daily opioid therapy in a primary care chronic pain sample.

Authors:  Kathryn Sullivan Dillie; Michael F Fleming; Marlon P Mundt; Michael T French
Journal:  J Am Board Fam Med       Date:  2008 Mar-Apr       Impact factor: 2.657

9.  Association of depression and anxiety alone and in combination with chronic musculoskeletal pain in primary care patients.

Authors:  Matthew J Bair; Jingwei Wu; Teresa M Damush; Jason M Sutherland; Kurt Kroenke
Journal:  Psychosom Med       Date:  2008-09-16       Impact factor: 4.312

Review 10.  When pain gets stuck: the evolution of pain chronification and treatment resistance.

Authors:  David Borsook; Andrew M Youssef; Laura Simons; Igor Elman; Christopher Eccleston
Journal:  Pain       Date:  2018-12       Impact factor: 7.926

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