Literature DB >> 34054385

C Hanriat1,2, C Barani1,2, A Mojallal2, F Braye1,2, S Brosset1,2.   

Abstract

Platelet rich plasma (PRP) has trophic functions due to a high concentration of growth factors and cytokines. These properties may be of therapeutic interest in the management of burn injuries. In preparation for a clinical study at the Lyon Burn Centre on PRP as an inducer of healing in burns, we carried out a review of the literature looking at the results of the use of this therapy. A review of the literature on the use of PRP for the treatment of burn injuries was performed by querying the PUBMED database using the keywords [platelet rich plasma] AND [burns]. Controlled clinical or pre-clinical studies in English or French were included. Eleven articles were identified, consisting of eight preclinical animal model studies and three clinical studies. These looked at the effects of PRP on the healing of burned areas whether they were grafted or not, on the improvement of neuropathic pain, and on distant skin trophicity. The results of recent preclinical studies show shorter epithelialization times thanks to PRP. In humans, a significant study (201 patients) validates its use in combination with thin skin grafts, and another shows benefits on distant cutaneous trophicity. In conclusion, the use of PRP topically or by injection under the skin has a potential benefit in the management of acute burns. A large-scale series validates its use in clinical practice.
Copyright © 2021 Euro-Mediterranean Council for Burns and Fire Disasters.

Entities:  

Year:  2021        PMID: 34054385      PMCID: PMC8126368     

Source DB:  PubMed          Journal:  Ann Burns Fire Disasters        ISSN: 1592-9558


  65 in total

1.  Autologous platelet-rich plasma mixed with purified fat graft in aesthetic plastic surgery.

Authors:  Valerio Cervelli; Ludovico Palla; Michele Pascali; Barbara De Angelis; Beniamino C Curcio; Pietro Gentile
Journal:  Aesthetic Plast Surg       Date:  2009-07-09       Impact factor: 2.326

Review 2.  Considerations on the use of platelet-rich plasma, specifically for burn treatment.

Authors:  Rose E Marck; Esther Middelkoop; Roelf S Breederveld
Journal:  J Burn Care Res       Date:  2014 May-Jun       Impact factor: 1.845

3.  Efficacy of Lyophilised Platelet-Rich Plasma Powder on Healing Rate in Patients With Deep Second Degree Burn Injury: A Prospective Double-Blind Randomized Clinical Trial.

Authors:  Chi-Yung Yeung; Pai-Shan Hsieh; Lin-Gwei Wei; Li-Chuan Hsia; Lien-Guo Dai; Keng-Yen Fu; Niann-Tzyy Dai
Journal:  Ann Plast Surg       Date:  2018-02       Impact factor: 1.539

4.  Acute thrombocytopenic crisis following burns complicated by staphylococcal septicaemia.

Authors:  A George; R L Bang; A R Lari; R K Gang
Journal:  Burns       Date:  2001-02       Impact factor: 2.744

5.  Scanning electron microscopy and microbiological evaluation of equine burn wound repair after platelet-rich plasma gel treatment.

Authors:  Felipe B Maciel; Rafael DeRossi; Tiago J C Módolo; Ronaldo C Pagliosa; Cássia R J Leal; Angela A S T Delben
Journal:  Burns       Date:  2012-06-07       Impact factor: 2.744

6.  Platelet quantification and growth factor analysis from platelet-rich plasma: implications for wound healing.

Authors:  Barry L Eppley; Jennifer E Woodell; Joel Higgins
Journal:  Plast Reconstr Surg       Date:  2004-11       Impact factor: 4.730

7.  Activation, function and content of platelets in burn patients.

Authors:  Roos E Marck; Ivo van der Bijl; Herbert Korsten; Jos Lorinser; Dirk de Korte; Esther Middelkoop
Journal:  Platelets       Date:  2018-03-19       Impact factor: 3.862

8.  [Use of platelet-rich plasma in major maxillary sinus augmentation].

Authors:  G Moro; V Casini; A Bastieri
Journal:  Minerva Stomatol       Date:  2003-06

9.  Use of platelet-rich plasma in deep second- and third-degree burns.

Authors:  Neil Grant Venter; Ruy Garcia Marques; Jeanine Salles Dos Santos; Andréa Monte-Alto-Costa
Journal:  Burns       Date:  2016-01-25       Impact factor: 2.744

10.  Growth Factor Quantification of Platelet-Rich Plasma in Burn Patients Compared to Matched Healthy Volunteers.

Authors:  Roos E Marck; Kim L M Gardien; Marcel Vlig; Roelf S Breederveld; Esther Middelkoop
Journal:  Int J Mol Sci       Date:  2019-01-12       Impact factor: 5.923

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