Literature DB >> 34054272

Colorectal Resection in Transplant Centers Benefits Kidney But Not Pancreas Transplant Recipients.

Lauren Weaver1, Afshin Parsikia2, Jorge Ortiz3.   

Abstract

As graft and patient survival rates improve, transplant recipients are likely to undergo colorectal surgery in their lifetime. Current literature on the surgical outcomes of colorectal resection in kidney and pancreas transplant recipients is sparse. This investigation identifies areas of surgical risk for kidney, pancreas, and pancreas-kidney transplant recipients undergoing colorectal resection at transplant and teaching centers. Multivariate logistic regression and linear regression tests computed odds ratios (OR) and coefficients of the linear regression using National Inpatient Sample data from 2005 to 2014 to identify differences in mortality, morbidity, length of stay (LOS), and total hospital charges among people with pancreas transplant alone (PTx), kidney transplant alone (KTx), pancreas and kidney transplant (PKTx), and nontransplant (non-Tx) undergoing colorectal resection in transplant and teaching centers. Of the 2,737,454 individuals who underwent colorectal resection, 138 PTx, 3,874 KTx, 130 PKTx, and 2,733,312 non-Tx met the inclusion criteria. Overall KTx, PTx, and PKTx were not more likely to suffer a mortality. However, PTx were more likely to suffer a mortality in transplant and teaching centers. Overall, PTx and PKTx had significantly higher morbidity odds ratios (PTx OR: 2.268, p  = 0.002; PKTx OR: 2.578, p  < 0.001) along with longer LOS and higher total hospital charges. KTx incurred no increased morbidity risk in transplant centers. Surgeons and transplant recipients should be aware of the increased morbidity and mortality risks when considering colorectal resection at different center types. International College of Angiology. This article is published by Thieme.

Entities:  

Keywords:  colectomy; colorectal resection; kidney transplant; pancreas transplant; teaching center; transplant center

Year:  2021        PMID: 34054272      PMCID: PMC8159591          DOI: 10.1055/s-0041-1727137

Source DB:  PubMed          Journal:  Int J Angiol        ISSN: 1061-1711


  20 in total

1.  Reduced perioperative death following laparoscopic colorectal resection: results of an international observational study.

Authors:  A Munasinghe; B Singh; N Mahmoud; M Joy; D C Chang; F Penninckx; O Faiz
Journal:  Surg Endosc       Date:  2015-03-12       Impact factor: 4.584

2.  Pancreas Transplantation of US and Non-US Cases from 2005 to 2014 as Reported to the United Network for Organ Sharing (UNOS) and the International Pancreas Transplant Registry (IPTR).

Authors:  Angelika C Gruessner; Rainer W G Gruessner
Journal:  Rev Diabet Stud       Date:  2016-03-14

3.  Effects of chronic immunosuppression on long-term oncologic outcomes for colorectal cancer patients undergoing surgery.

Authors:  Wisam Khoury; Ian C Lavery; Ravi P Kiran
Journal:  Ann Surg       Date:  2011-02       Impact factor: 12.969

4.  Risk of Colorectal Cancer After Solid Organ Transplantation in the United States.

Authors:  M Safaeian; H A Robbins; S I Berndt; C F Lynch; J F Fraumeni; E A Engels
Journal:  Am J Transplant       Date:  2016-01-05       Impact factor: 8.086

5.  Severe diverticulitis after heart, lung, and heart-lung transplantation.

Authors:  Raffi A Qasabian; Alan P Meagher; Regent Lee; Greg J Dore; Anne Keogh
Journal:  J Heart Lung Transplant       Date:  2004-07       Impact factor: 10.247

Review 6.  Effect of red cell transfusions on future kidney transplantation.

Authors:  Gregorio T Obrador; Iain C Macdougall
Journal:  Clin J Am Soc Nephrol       Date:  2012-10-18       Impact factor: 8.237

7.  Risk Associated With Complications and Mortality After Urgent Surgery vs Elective and Emergency Surgery: Implications for Defining "Quality" and Reporting Outcomes for Urgent Surgery.

Authors:  Matthew G Mullen; Alex D Michaels; J Hunter Mehaffey; Christopher A Guidry; Florence E Turrentine; Traci L Hedrick; Charles M Friel
Journal:  JAMA Surg       Date:  2017-08-01       Impact factor: 14.766

Review 8.  Emergency abdominal surgery after solid organ transplantation: a systematic review.

Authors:  Nicola de'Angelis; Francesco Esposito; Riccardo Memeo; Vincenzo Lizzi; Aleix Martìnez-Pérez; Filippo Landi; Pietro Genova; Fausto Catena; Francesco Brunetti; Daniel Azoulay
Journal:  World J Emerg Surg       Date:  2016-08-30       Impact factor: 5.469

9.  Colorectal Cancer Characteristics and Outcomes after Solid Organ Transplantation.

Authors:  Amit Merchea; Faisal Shahjehan; Kristopher P Croome; Jordan J Cochuyt; Zhuo Li; Dorin T Colibaseanu; Pashtoon Murtaza Kasi
Journal:  J Oncol       Date:  2019-02-28       Impact factor: 4.375

10.  Cancer risk following organ transplantation: a nationwide cohort study in Sweden.

Authors:  J Adami; H Gäbel; B Lindelöf; K Ekström; B Rydh; B Glimelius; A Ekbom; H-O Adami; F Granath
Journal:  Br J Cancer       Date:  2003-10-06       Impact factor: 7.640

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