Literature DB >> 34053060

Cytotoxic T Lymphocytes (CTLs) and Kidney Transplantation: An Overview.

Federica Rascio1, Paola Pontrelli2, Giuseppe Grandaliano3,4.   

Abstract

Involvement of T lymphocytes in kidney transplantation is a well-developed topic; however, most of the scientific interest focused on the different type of CD4+ lymphocyte subpopulations. Few authors, instead, investigated the role of CD8+ T cells in renal transplantation and how deleterious they can be to long-term allograft survival. Recently, there has been a renewed interest in the CD8+ T cells involvement in the transplantation field with the aim to investigate the immunological mechanisms underlying the infiltration of CD8+ T cells and their biological functions in human kidney allografts. The purpose of the present review is to highlight the role of allo-reactive cytotoxic T lymphocytes (CTLs) CD8+ subset in allograft kidney recipients and their related clinical complications.

Entities:  

Keywords:  Adaptive immunity; Cytokines; Cytotoxic T lymphocytes (CTLs); Cytotoxic-associated transcripts (CATs); Immunosuppression; Kidney transplantation; Rejection

Year:  2021        PMID: 34053060     DOI: 10.1007/978-1-0716-1507-2_14

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  59 in total

1.  Depletion of CD8 memory T cells for induction of tolerance of a previously transplanted kidney allograft.

Authors:  I Koyama; O Nadazdin; S Boskovic; T Ochiai; R N Smith; M Sykes; H Sogawa; T Murakami; T B Strom; R B Colvin; D H Sachs; G Benichou; A B Cosimi; T Kawai
Journal:  Am J Transplant       Date:  2007-02-07       Impact factor: 8.086

2.  Expansion of highly differentiated cytotoxic terminally differentiated effector memory CD8+ T cells in a subset of clinically stable kidney transplant recipients: a potential marker for late graft dysfunction.

Authors:  Michelle Yap; Françoise Boeffard; Emmanuel Clave; Annaick Pallier; Richard Danger; Magali Giral; Jacques Dantal; Yohann Foucher; Cécile Guillot-Gueguen; Antoine Toubert; Jean-Paul Soulillou; Sophie Brouard; Nicolas Degauque
Journal:  J Am Soc Nephrol       Date:  2014-03-20       Impact factor: 10.121

Review 3.  Molecules in medicine mini review: the αβ T cell receptor.

Authors:  Eric T Clambey; Bennett Davenport; John W Kappler; Philippa Marrack; Dirk Homann
Journal:  J Mol Med (Berl)       Date:  2014-05-22       Impact factor: 4.599

4.  Phenotypically and functionally distinct CD8+ lymphocyte populations in long-term drug-free tolerance and chronic rejection in human kidney graft recipients.

Authors:  Dominique Baeten; Stéphanie Louis; Christophe Braud; Cécile Braudeau; Caroline Ballet; Frédéric Moizant; Annaik Pallier; Magali Giral; Sophie Brouard; Jean-Paul Soulillou
Journal:  J Am Soc Nephrol       Date:  2005-12-07       Impact factor: 10.121

Review 5.  The role of CD8+ T cells during allograft rejection.

Authors:  V Bueno; J O M Pestana
Journal:  Braz J Med Biol Res       Date:  2002-11       Impact factor: 2.590

6.  Terminally differentiated CD8+ Temra cells are associated with the risk for acute kidney allograft rejection.

Authors:  Michiel G H Betjes; Ruud W J Meijers; Elly A de Wit; Willem Weimar; Nicolle H R Litjens
Journal:  Transplantation       Date:  2012-07-15       Impact factor: 4.939

Review 7.  Allorecognition by T Lymphocytes and Allograft Rejection.

Authors:  Jose Marino; Joshua Paster; Gilles Benichou
Journal:  Front Immunol       Date:  2016-12-14       Impact factor: 7.561

8.  A higher risk of acute rejection of human kidney allografts can be predicted from the level of CD45RC expressed by the recipients' CD8 T cells.

Authors:  Laurence Ordonez; Isabelle Bernard; Marianne Chabod; Jean-François Augusto; Valerie Lauwers-Cances; Christelle Cristini; Maria-Cristina Cuturi; Jean-François Subra; Abdelhadi Saoudi
Journal:  PLoS One       Date:  2013-07-24       Impact factor: 3.240

9.  Increased numbers of circulating CD8 effector memory T cells before transplantation enhance the risk of acute rejection in lung transplant recipients.

Authors:  David San Segundo; María Ángeles Ballesteros; Sara Naranjo; Felipe Zurbano; Eduardo Miñambres; Marcos López-Hoyos
Journal:  PLoS One       Date:  2013-11-13       Impact factor: 3.240

Review 10.  Targeting CD8 T-Cell Metabolism in Transplantation.

Authors:  Michelle Yap; Sophie Brouard; Claire Pecqueur; Nicolas Degauque
Journal:  Front Immunol       Date:  2015-10-23       Impact factor: 7.561

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