Literature DB >> 34052830

Bardoxolone and bardoxolone methyl, two Nrf2 activators in clinical trials, inhibit SARS-CoV-2 replication and its 3C-like protease.

Qi Sun1, Fei Ye2, Hao Liang1, Hongbo Liu1, Chunmei Li3, Roujian Lu2, Baoying Huang2, Li Zhao2, Wenjie Tan4, Luhua Lai5,6.   

Abstract

Entities:  

Year:  2021        PMID： 34052830     DOI： 10.1038/s41392-021-00628-x

Source DB:  PubMed          Journal:  Signal Transduct Target Ther        ISSN： 2059-3635


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  7 in total

1.  Does atmospheric dimethyldiselenide play a role in reducing COVID-19 mortality?

Authors:  Jinsong Zhang; Ethan Will Taylor; Kate Bennett; Margaret P Rayman
Journal:  Gondwana Res       Date:  2022-06-06       Impact factor: 6.151

Review 2.  Untapping host-targeting cross-protective efficacy of anticoagulants against SARS-CoV-2.

Authors:  Brian F Niemeyer; Kambez H Benam
Journal:  Pharmacol Ther       Date:  2021-10-28       Impact factor: 13.400

3.  Nrf2 activation reprograms macrophage intermediary metabolism and suppresses the type I interferon response.

Authors:  Dylan G Ryan; Elena V Knatko; Alva M Casey; Jens L Hukelmann; Sharadha Dayalan Naidu; Alejandro J Brenes; Thanapon Ekkunagul; Christa Baker; Maureen Higgins; Laura Tronci; Efterpi Nikitopolou; Tadashi Honda; Richard C Hartley; Luke A J O'Neill; Christian Frezza; Angus I Lamond; Andrey Y Abramov; J Simon C Arthur; Doreen A Cantrell; Michael P Murphy; Albena T Dinkova-Kostova
Journal:  iScience       Date:  2022-01-30

Review 4.  Redox Homeostasis and Immune Alterations in Coronavirus Disease-19.

Authors:  Francesco Bellanti; Aurelio Lo Buglio; Gianluigi Vendemiale
Journal:  Biology (Basel)       Date:  2022-01-19

5.  Identification, optimization, and biological evaluation of 3-O-β-chacotriosyl ursolic acid derivatives as novel SARS-CoV-2 entry inhibitors by targeting the prefusion state of spike protein.

Authors:  Hui Li; Chen Cheng; Shanshan Shi; Yan Wu; Yongfeng Gao; Zhihao Liu; Mingjian Liu; Zhaodong Li; Lijian Huo; Xiaoyan Pan; Shuwen Liu; Gaopeng Song
Journal:  Eur J Med Chem       Date:  2022-05-07       Impact factor: 7.088

Review 6.  Clinical Research Progress of Small Molecule Compounds Targeting Nrf2 for Treating Inflammation-Related Diseases.

Authors:  Zhenzhen Zhai; Yanxin Huang; Yawei Zhang; Lili Zhao; Wen Li
Journal:  Antioxidants (Basel)       Date:  2022-08-12

Review 7.  Oxidative Stress in Arterial Hypertension (HTN): The Nuclear Factor Erythroid Factor 2-Related Factor 2 (Nrf2) Pathway, Implications and Future Perspectives.

Authors:  Daniela Maria Tanase; Alina Georgiana Apostol; Claudia Florida Costea; Claudia Cristina Tarniceriu; Ionut Tudorancea; Minela Aida Maranduca; Mariana Floria; Ionela Lacramioara Serban
Journal:  Pharmaceutics       Date:  2022-02-27       Impact factor: 6.321
  7 in total

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