Maoqing Jiang1,2, Ping Chen3, Rong Huang4, Jingfeng Zhang1,2, Jianjun Zheng5,6. 1. Ningbo PET/CT center, Hwa Mei Hospital, University of Chinese Academy of Sciences, Ningbo, China. 2. Ningbo Institute of Life and Health Industry, University of Chinese Academy of Sciences, Ningbo, China. 3. Department of Nephrology, Hwa Mei Hospital, University of Chinese Academy of Sciences, Ningbo, China. 4. Department of Pathology, Hwa Mei Hospital, University of Chinese Academy of Sciences, Ningbo, China. 5. Ningbo PET/CT center, Hwa Mei Hospital, University of Chinese Academy of Sciences, Ningbo, China. zhengjianjun@ucas.ac.cn. 6. Ningbo Institute of Life and Health Industry, University of Chinese Academy of Sciences, Ningbo, China. zhengjianjun@ucas.ac.cn.
Abstract
BACKGROUND: Primary pulmonary meningioma (PPM) is an extremely rare disease, which is often misdiagnosed as lung metastasis. Previous studies indicated that PPM usually showed homogeneous enhancement on enhanced CT and high uptake of 18F-fluorodeoxyglucose (18F-FDG) on positron emission tomography/CT (PET/CT). In this study, we report a case of PPM with atypical enhanced CT and 18F-FDG PET/CT features in a patient with rectal carcinoma. CASE PRESENTATION: A 70-year-old male was demonstrated to have rectal carcinoma by biopsy while a solitary pulmonary nodule (SPN) with well-defined edges measuring 13 × 13 × 15 mm was almost simultaneously found in the right lower robe on chest CT scan. Contrast-enhanced CT and PET/CT revealed mild centripetal enhancement of the nodule without accumulation of 18F-FDG. A thoracoscopic wedge resection of the right lower lobe was finally performed and histopathologic examinations and PET/CT imaging showed that the nodule was a PPM. CONCLUSION: PPM is a rare disease with heterogeneity not only in blood supply but also in glucose metabolism. 18F-FDG PET/CT may be an effective method for differentiating benign and malignant SPNs. The diagnosis of PPM depends on pathological and radiological examinations.
BACKGROUND:Primary pulmonary meningioma (PPM) is an extremely rare disease, which is often misdiagnosed as lung metastasis. Previous studies indicated that PPM usually showed homogeneous enhancement on enhanced CT and high uptake of 18F-fluorodeoxyglucose (18F-FDG) on positron emission tomography/CT (PET/CT). In this study, we report a case of PPM with atypical enhanced CT and 18F-FDG PET/CT features in a patient with rectal carcinoma. CASE PRESENTATION: A 70-year-old male was demonstrated to have rectal carcinoma by biopsy while a solitary pulmonary nodule (SPN) with well-defined edges measuring 13 × 13 × 15 mm was almost simultaneously found in the right lower robe on chest CT scan. Contrast-enhanced CT and PET/CT revealed mild centripetal enhancement of the nodule without accumulation of 18F-FDG. A thoracoscopic wedge resection of the right lower lobe was finally performed and histopathologic examinations and PET/CT imaging showed that the nodule was a PPM. CONCLUSION: PPM is a rare disease with heterogeneity not only in blood supply but also in glucose metabolism. 18F-FDG PET/CT may be an effective method for differentiating benign and malignant SPNs. The diagnosis of PPM depends on pathological and radiological examinations.
Authors: Catherine Weber; Sophie Pautex; Gilbert B Zulian; Marc Pusztaszeri; Johannes Alexander Lobrinus Journal: Virchows Arch Date: 2013-02-27 Impact factor: 4.064