Literature DB >> 34047948

Kuanxiong Aerosol () in Treatment of Angina Pectoris: A Literature Review and Network Pharmacology.

Yu-Zhuo Zhang1,2, Rui-Xiang Zeng1,2,3, Yuan-Shen Zhou2,3, Min-Zhou Zhang4,5,6.   

Abstract

Angina pectoris (AP) is the most common symptom of cardiovascular diseases, which seriously affects the quality of life in cardiovascular patients. Kuanxiong (KX) Aerosol (), a compound preparation that consists of 5 traditional Chinese medicines: Herba Asari , Rhizoma Alpiniae Officinarum, Lignum Santali Albi, Fructus Piperis Longi, and Borneolum, has been used in the treatment of AP for many years, exhibiting a significant curative effect and less side-effect. For the convenience and comprehensive understanding of KX Aerosol, this review systematically summarizes evidence on KX Aerosol in the treatment of AP including the pharmacological effects of its composition, clinical research, animal experiments, and network pharmacology prediction. Meanwhile, we highlight the research limitation of KX Aerosol at present. This review may guide the clinical application of KX Aerosol and further provide a reference for the research of AP.

Entities:  

Keywords:  Kuanxiong Aerosol; angina pectoris; clinical application; network pharmacology; pharmacology

Year:  2021        PMID: 34047948     DOI: 10.1007/s11655-021-2867-y

Source DB:  PubMed          Journal:  Chin J Integr Med        ISSN: 1672-0415            Impact factor:   1.978


  63 in total

1.  Antinociceptive effect of methyleugenol on formalin-induced hyperalgesia in mice.

Authors:  Shingo Yano; Yasuyuki Suzuki; Mitsutoshi Yuzurihara; Yoshio Kase; Shuichi Takeda; Satoshi Watanabe; Masaki Aburada; Ken-Ichi Miyamoto
Journal:  Eur J Pharmacol       Date:  2006-09-23       Impact factor: 4.432

2.  Effect of Kuanxiong Aerosol () on Patients with Angina Pectoris: A Non-inferiority Multi-center Randomized Controlled Trial.

Authors:  Qiao-Ning Yang; Rui-Na Bai; Guo-Ju Dong; Chang-Jiang Ge; Jing-Min Zhou; Li Huang; Yan He; Jun Wang; Ai-Hua Ren; Zhan-Quan Huang; Guang-Li Zhu; Shu Lu; Shang-Quan Xiong; Shao-Xiang Xian; Zhi-Jun Zhu; Da-Zhuo Shi; Shu-Zheng Lu; Li-Zhi Li; Ke-Ji Chen
Journal:  Chin J Integr Med       Date:  2018-02-13       Impact factor: 1.978

3.  Immediate effect of Kuan-xiong aerosol in the treatment of anginal attacks.

Authors:  S K Guo; K J Chen; W L Weng; W Q Zhang; Y Q Yu
Journal:  Planta Med       Date:  1983-02       Impact factor: 3.352

4.  Asiasari sieboldii suppresses inflammatory mediators through the induction of hemeoxygenase-1 expression in RAW264.7 cells.

Authors:  Jin-Ah Lee; Mee-Young Lee; Chang Seob Seo; Hyekyung Ha; Hoyoung Lee; Jung-Hoon Kim; Hyeun Kyoo Shin
Journal:  Immunopharmacol Immunotoxicol       Date:  2011-06-28       Impact factor: 2.730

Review 5.  The Global Burden of Disease Study and the Preventable Burden of NCD.

Authors:  Catherine P Benziger; Gregory A Roth; Andrew E Moran
Journal:  Glob Heart       Date:  2016-12

6.  Invasive evaluation of patients with angina in the absence of obstructive coronary artery disease.

Authors:  Bong-Ki Lee; Hong-Seok Lim; William F Fearon; Andy S Yong; Ryotaro Yamada; Shigemitsu Tanaka; David P Lee; Alan C Yeung; Jennifer A Tremmel
Journal:  Circulation       Date:  2015-02-20       Impact factor: 29.690

Review 7.  Expert consensus document: A 'diamond' approach to personalized treatment of angina.

Authors:  Roberto Ferrari; Paolo G Camici; Filippo Crea; Nicolas Danchin; Kim Fox; Aldo P Maggioni; Athanasios J Manolis; Mario Marzilli; Giuseppe M C Rosano; José L Lopez-Sendon
Journal:  Nat Rev Cardiol       Date:  2017-09-07       Impact factor: 32.419

8.  Mechanism of anti-nociceptive effects of Asarum sieboldii Miq. radix: potential role of bradykinin, histamine and opioid receptor-mediated pathways.

Authors:  Sung-Jin Kim; Cheng Gao Zhang; Jung Taek Lim
Journal:  J Ethnopharmacol       Date:  2003-09       Impact factor: 4.360

9.  Comparative analysis of two species of Asari Radix et Rhizoma by electronic nose, headspace GC-MS and chemometrics.

Authors:  Chen Li; Feng Xu; Chen Cao; Ming-Ying Shang; Cui-Ying Zhang; Jie Yu; Guang-Xue Liu; Xuan Wang; Shao-Qing Cai
Journal:  J Pharm Biomed Anal       Date:  2013-08-07       Impact factor: 3.935

10.  Chronic refractory angina pectoris: recent progress and remaining challenges.

Authors:  Johannes Waltenberger
Journal:  Eur Heart J       Date:  2017-09-01       Impact factor: 29.983

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