Literature DB >> 34047088

[Structural Chinese medicine: new research field on pharmacodynamic substance basis of traditional Chinese medicine].

Hong-Zhi Qiao1, Liu-Qing DI2, Qi-Neng Ping3, Li-Hong Hu4.   

Abstract

The research on the pharmacodynamic substance basis of traditional Chinese medicine(TCM) is a key scientific issue for the inheritance and development of TCM. At present, a large number of remarkable achievements have been made in the field of chemical components in Chinese medicine, however, another important aspect, namely the physical structure and mode of action of the multi-component assembly of TCM, has not been clearly understood and deeply studied. From the bottleneck of restricting material ba-sic research, we objectively analyzed the common cause of the existing problems. Based on the new discoveries and advances of active substances from TCM emerging in recent years, we extracted and summarized the concept of structural Chinese medicine, elaborated the basic ideas, main features and research modes, hoping to provide theoretical and practical references for the study on the pharmacodynamic substance basis and other research fields of TCM.

Entities:  

Keywords:  carbonized traditional Chinese medicine; decoction; exosomes; nanotechnology; pharmacodynamic substance; phase state; quality control; structural Chinese medicine; supramolecules; traditional Chinese medicine preparation; unification of medicines and excipients

Mesh:

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Year:  2021        PMID: 34047088     DOI: 10.19540/j.cnki.cjcmm.20210129.601

Source DB:  PubMed          Journal:  Zhongguo Zhong Yao Za Zhi        ISSN: 1001-5302


  3 in total

Review 1.  [Progress and prospect of application of traditional Chinese medicine fingerprint (specific chromatogram) in Chinese Pharmacopoeia (2010-2020)].

Authors:  H Yan; C Zou
Journal:  Nan Fang Yi Ke Da Xue Xue Bao       Date:  2022-01-20

Review 2.  Supramolecular assemblies based on natural small molecules: Union would be effective.

Authors:  Yong Hou; Linjun Zou; Qinglong Li; Meiying Chen; Haonan Ruan; Zhaocui Sun; Xudong Xu; Junshan Yang; Guoxu Ma
Journal:  Mater Today Bio       Date:  2022-06-15

Review 3.  Unraveling the mystery of efficacy in Chinese medicine formula: New approaches and technologies for research on pharmacodynamic substances.

Authors:  Yaolei Li; Zhijian Lin; Yu Wang; Shanshan Ju; Hao Wu; Hongyu Jin; Shuangcheng Ma; Bing Zhang
Journal:  Arab J Chem       Date:  2022-09-27       Impact factor: 6.212

  3 in total

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