Jennifer Cunningham-Erves1, Tilicia L Mayo-Gamble2, Pamela C Hull3,4, Tao Lu5, Claudia Barajas4, Caree R McAfee3, Maureen Sanderson6, Juan R Canedo5,7, Katina Beard8, Consuelo H Wilkins9,10,11. 1. Department of Internal Medicine, Meharry Medical College, 1005 Dr. D. B. Todd Jr. Blvd., Nashville, TN, 37208, USA. jerves@mmc.edu. 2. Department of Health Policy and Community Health, Georgia Southern University, Statesboro, GA, USA. 3. Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. 4. Vanderbilt University Medical Center, Vanderbilt Ingram Cancer Center, Nashville, TN, USA. 5. School of Graduate Studies, Meharry Medical College, Nashville, TN, USA. 6. Department of Family and Community Medicine, Meharry Medical College, Nashville, TN, USA. 7. Progreso Community Center, Nashville, TN, USA. 8. Matthew Walker Community Health Center, Nashville, TN, USA. 9. Department of Internal Medicine, Meharry Medical College, 1005 Dr. D. B. Todd Jr. Blvd., Nashville, TN, 37208, USA. 10. Meharry-Vanderbilt Alliance, Nashville, TN, USA. 11. Vanderbilt University Medical Center, Office of Health Equity, Nashville, TN, USA.
Abstract
AIM: Culturally-appropriate, educational programs are recommended to improve cancer clinical trial participation among African Americans and Latinos. This study investigated the effect of a culturally-appropriate, educational program on knowledge, trust in medical researchers, and intent for clinical trial participation among African Americans and Latinos in Middle Tennessee. METHOD: Trained community health educators delivered a 30-min presentation with video testimonials to 198 participants in 13 town halls. A pre-post survey design was used to evaluate the intervention among 102 participants who completed both pre- and post-surveys one to two weeks after the session. RESULTS: Paired-sample t-test showed significant increases in unadjusted mean scores for knowledge (p < 0.001), trust in medical researchers (p < 0.001), and willingness to participate in clinical trials (p = 0.003) after the town halls in the overall sample. After adjusting for gender and education, all three outcomes remained significant for the overall sample (knowledge: p < 0.001; trust in medical researchers: p < 0.001; willingness: p = 0.001) and for African Americans (knowledge: p < 0.001; trust in medical researchers: p = 0.007; willingness: p = 0.005). However, willingness to participate was no longer significant for Latinos (knowledge: p < 0.001; trust in medical researchers: p = 0.034; willingness: p = 0.084). CONCLUSIONS: The culturally-appropriate, educational program showed promising results for short-term, clinical trial outcomes. Further studies should examine efficacy to improve research participation outcomes.
AIM: Culturally-appropriate, educational programs are recommended to improve cancer clinical trial participation among African Americans and Latinos. This study investigated the effect of a culturally-appropriate, educational program on knowledge, trust in medical researchers, and intent for clinical trial participation among African Americans and Latinos in Middle Tennessee. METHOD: Trained community health educators delivered a 30-min presentation with video testimonials to 198 participants in 13 town halls. A pre-post survey design was used to evaluate the intervention among 102 participants who completed both pre- and post-surveys one to two weeks after the session. RESULTS: Paired-sample t-test showed significant increases in unadjusted mean scores for knowledge (p < 0.001), trust in medical researchers (p < 0.001), and willingness to participate in clinical trials (p = 0.003) after the town halls in the overall sample. After adjusting for gender and education, all three outcomes remained significant for the overall sample (knowledge: p < 0.001; trust in medical researchers: p < 0.001; willingness: p = 0.001) and for African Americans (knowledge: p < 0.001; trust in medical researchers: p = 0.007; willingness: p = 0.005). However, willingness to participate was no longer significant for Latinos (knowledge: p < 0.001; trust in medical researchers: p = 0.034; willingness: p = 0.084). CONCLUSIONS: The culturally-appropriate, educational program showed promising results for short-term, clinical trial outcomes. Further studies should examine efficacy to improve research participation outcomes.
Authors: Grace C Hillyer; Melissa Beauchemin; Dawn L Hershman; Moshe Kelsen; Frances L Brogan; Rossy Sandoval; Karen M Schmitt; Andria Reyes; Mary Beth Terry; Andrew B Lassman; Gary K Schwartz Journal: Clin Trials Date: 2020-02-03 Impact factor: 2.486
Authors: Lauren M Hamel; Louis A Penner; Terrance L Albrecht; Elisabeth Heath; Clement K Gwede; Susan Eggly Journal: Cancer Control Date: 2016-10 Impact factor: 3.302
Authors: Kimberly D Miller; Ann Goding Sauer; Ana P Ortiz; Stacey A Fedewa; Paulo S Pinheiro; Guillermo Tortolero-Luna; Dinorah Martinez-Tyson; Ahmedin Jemal; Rebecca L Siegel Journal: CA Cancer J Clin Date: 2018-10-04 Impact factor: 508.702
Authors: Grace Ann Hanvey; Adaixa Padron; Elizabeth L Kacel; Gabriel Cartagena; Kelsey C Bacharz; Christina S McCrae; Michael E Robinson; Lori B Waxenberg; Michael H Antoni; Richard B Berry; Gregory S Schultz; Jacqueline Castagno; Deidre B Pereira Journal: J Clin Transl Sci Date: 2022-04-01